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Merck

ADRA2C

adrenoceptor alpha 2C

別名:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Species:
UniProtKB ID:
遺伝子ID:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

Custom & Knockdown Gene Products

Small Molecule - Agonist

製品番号
詳細
Species
キシラジン 塩酸塩, ≥99.0% (HPLC),
Species
human
(−)-3-(3,4-ジヒドロキシフェニル)-2-メチル-L-アラニン セスキ水和物, 99%,
Species
human
グアナベンズ 酢酸塩, powder,
Species
human
グアンファシン 塩酸塩, ≥98% (HPLC),
Species
human
メチル-DOPA セスキ水和物, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
ヨヒンビン 塩酸塩, ≥98% (HPLC), powder,
Species
human
イダゾキサン 塩酸塩, ,
Species
human
RX 821002 塩酸塩, solid, ≥98% (HPLC),
Species
human
UK 14,304, ,
Species
human
ミルタザピン, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
Anti-ADRA2C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-Alpha-2C antibody produced in mouse, clone S330A-80, purified immunoglobulin,
交差性
human, mouse
アプリケーション
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Apc antibody produced in mouse, clone S330A-80, purified immunoglobulin,
交差性
human, mouse
アプリケーション
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Biotin antibody produced in mouse, clone S330A-80, purified immunoglobulin,
交差性
human, mouse
アプリケーション
immunocytochemistry
western blot

Small Molecule - Blocker

製品番号
詳細
Species
ミアンセリン 塩酸塩, ,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
UK 14,304, ,
Species
human
(−)-ノルエピネフリン, ≥98%, crystalline,
Species
human, rat
ハロペリドール, powder,
Species
human, rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Adra2c,
Species
mouse