1604803

Ritonavir

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
• Formula empirica (notazione di Hill): C₃₇H₄₈N₆O₅S₂
• Numero CAS: 155213-67-5
• Peso molecolare: 720.94
• Numero MDL: MFCD08694944
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Origine biologica: synthetic
• Grado: pharmaceutical primary standard
• agenzia: USP
• Tensione di vapore: <0.0000001 kPa ( 25 °C)
• Famiglia di API: ritonavir
• Stato: powder
• Confezionamento: pkg of 200 mg
• Produttore/marchio commerciale: USP
• Condizioni di stoccaggio: protect from light
• Colore: white to tan
• Solubilità: acetonitrile: slightly soluble; ethanol: freely soluble; methanol: freely soluble; methylene chloride: freely soluble; water: practically insoluble
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: [s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C
• InChI: 1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1; NCDNCNXCDXHOMX-XGKFQTDJSA-N

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.[1]

Applicazioni

Ritonavir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Ritonavir Capsules
• Ritonavir Tablets
• Ritonavir Oral Solution
• Lopinavir and Ritonavir Tablets
• Lopinavir and Ritonavir Oral Solution

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302 + H312 + H332
• Consigli di prudenza: P261 - P280 - P301 + P312 + P330
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable