X7375

Xantina

≥99%

• Sinonimo/i: 2,6-diidrossipurina
• Formula empirica (notazione di Hill): C₅H₄N₄O₂
• Numero CAS: 69-89-6
• Peso molecolare: 152.11
• Beilstein: 8733
• Numero CE: 200-718-6
• Numero MDL: MFCD00078453
• Codice UNSPSC: 41106305
• ID PubChem: 24902156
• NACRES: NA.51

Proprietà

• Origine biologica: synthetic (organic)
• Saggio: ≥99%
• Forma fisica: powder
• Solubilità: 1 M NaOH: soluble 50 mg/mL, clear to slightly hazy; NH₄OH: freely soluble; NaOH: freely soluble
• Stringa SMILE: O=C1NC(=O)c2nc[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11); LRFVTYWOQMYALW-UHFFFAOYSA-N

Descrizione

Descrizione generale

Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid. Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.

Applicazioni

Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay. It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells and algal cells.

Azioni biochim/fisiol

A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples. Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves