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T2803

7-Ethoxy-4-(trifluoromethyl)coumarin

≥98% (TLC), powder

Sinonimo/i:

Ethyl 4-(trifluoromethyl)umbelliferyl ether

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Taglio della confezioneSKUDisponibilitàPrezzo
5 mg
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328,00 €
278,80 €

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C12H9F3O3
Numero CAS:
Peso molecolare:
258.19
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Beilstein/REAXYS Number:
8555209

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Nome del prodotto

7-Ethoxy-4-(trifluoromethyl)coumarin, ≥98% (TLC)

Quality Level

assay

≥98% (TLC)

form

powder

solubility

chloroform: 100 mg/mL, clear, colorless (Soluble in chloroform, methanol, and DMSO.)

fluorescence

λex 333 nm; λem 415 nm in methanol

storage temp.

−20°C

SMILES string

CCOc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C12H9F3O3/c1-2-17-7-3-4-8-9(12(13,14)15)6-11(16)18-10(8)5-7/h3-6H,2H2,1H3

InChI key

OLHOIERZAZMHGK-UHFFFAOYSA-N

Features and Benefits

7-Ethoxy-4-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P-450 catalyzed O-de-ethylation.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Questo articolo
T3165N0252SML2821
DiFMUP ≥98% (HPLC)

Sigma-Aldrich

SML2821

DiFMUP

assay

≥98% (TLC)

assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

solubility

chloroform: 100 mg/mL, clear, colorless (Soluble in chloroform, methanol, and DMSO.)

solubility

acetone: 50 mg/mL, clear, colorless to faintly yellow

solubility

chloroform: soluble 100 mg/mL, colorless to faintly yellow

solubility

DMSO: 2 mg/mL, clear

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

room temp

fluorescence

λex 333 nm; λem 415 nm in methanol

fluorescence

λex 333 nm; λem 416 nm in methanol

fluorescence

-

fluorescence

-


Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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J G DeLuca et al.
Biochemical pharmacology, 37(9), 1731-1739 (1988-05-01)
The microsomal O-deethylation of a novel coumarin analog, 7-ethoxy-4-trifluoromethylcoumarin (EFC), to a fluorescent product was characterized. Results indicate that this analog provides a rapid, convenient and highly sensitive means to assay cytochrome P-450-mediated metabolism. Like microsomal 7-ethoxycoumarin (7-EC) O-deethylation, EFC
Thomas Van Leeuwen et al.
Pest management science, 62(5), 425-433 (2006-03-22)
Tetranychus urticae Koch has recently developed resistance to chlorfenapyr in Australia and Japan, but no attempt has yet been made to describe the biochemical mechanisms involved in chlorfenapyr resistance. In this study a laboratory-selected chlorfenapyr-resistant strain was investigated. Resistance to
Maori Mitsuda et al.
Protein expression and purification, 46(2), 401-405 (2005-11-29)
Improvement of CYP2B6 expression was examined by co-expression with molecular chaperones GroES/EL. Although a CO-reduced difference spectrum was not detected in Escherichia coli transformed only by the CYP2B6-expressing vector, co-expression of GroES/EL resulted in high-level expression which reached over 2000



Numero articolo commerciale globale

SKUGTIN
T2803-5MG04061832910253

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