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Merck
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Documenti fondamentali

SRP6161

Sigma-Aldrich

FGF-7 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

Sinonimo/i:

Fibroblast growth factor 7, HBGF-7, Heparin-binding growth factor 7, KGF, Keratinocyte growth factor

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About This Item

Codice UNSPSC:
12352202
NACRES:
NA.32

Origine biologica

human

Ricombinante

expressed in human cells

Saggio

≥95% (SDS-PAGE)

Stato

lyophilized

PM

(17 and 30 kDa, monomer, glycosylated)

Confezionamento

pkg of 10 μg

tecniche

cell culture | mammalian: suitable

N° accesso NCBI

P21781

N° accesso UniProt

P21781

Condizioni di spedizione

dry ice

Temperatura di conservazione

−70°C

Informazioni sul gene

human ... FGF7(2252)

Descrizione generale

Fibroblast growth factor-7 (FGF-7) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities. The gene encoding this protein is localized on human chromosome 15q21.1.[1][2]

Azioni biochim/fisiol

Fibroblast growth factor (FGF) family members are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. This protein associates with and activates fibroblast growth factor receptors (FGFRs). Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.[3][4]

Stato fisico

Lyophilized from a PBS solution.

Nota sulla preparazione

Centrifuge the vial prior to opening.

Ricostituzione

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
7G08L64500
6M02L64500

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A family-based association study after genome-wide linkage analysis identified two genetic loci for renal function in a Mongolian population.
Park H
Kidney International, 83(2), 285-292 (2013)
The Fibroblast Growth Factor signaling pathway.
Ornitz DM and Itoh N
Wiley Interdisciplinary Reviews. Systems Biology and Medicine, 4(3), 215-266 (2015)
Krijn K Dijkstra et al.
Cell reports, 31(5), 107588-107588 (2020-05-07)
Clinical implementation of tumor organoids for personalized medicine requires that pure tumor organoids can be reliably established. Here, we present our experience with organoid cultures from >70 non-small cell lung cancer (NSCLC) samples. We systematically evaluate several methods to identify
Laxmi Yeruva et al.
mBio, 5(3), e01241-e01214 (2014-06-26)
It is not currently possible to predict the probability of whether a woman with a chlamydial genital infection will develop pelvic inflammatory disease (PID). To determine if specific biomarkers may be associated with distinct chlamydial pathotypes, we utilized two Chlamydia
Xiao-Jing Zhu et al.
PLoS genetics, 10(10), e1004687-e1004687 (2014-10-21)
Epidermal stratification of the mammalian skin requires proliferative basal progenitors to generate intermediate cells that separate from the basal layer and are replaced by post-mitotic cells. Although Wnt signaling has been implicated in this developmental process, the mechanism underlying Wnt-mediated
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Articoli

Growth Factors in Stem Cell Biology

Role of growth factors in stem cell differentiation and various growth factors for your research at sigmaaldrich.com

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