SRP3325

Uterglobin Peptide

≥98% (HPLC), human recombinant, expressed in E. coli

• Sinonimo/i: Clara cell phospholipid-binding protein, Secretoglobin family 1A member 1, Urinary protein 1
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Nome del prodotto: UTERGLOBULIN human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
• Origine biologica: human
• Ricombinante: expressed in E. coli
• Saggio: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Stato: lyophilized
• PM: 8.0 kDa
• Confezionamento: pkg of 50 μg
• Impurezze: endotoxin, tested
• N° accesso UniProt: P11684
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... SCGB1A1(7356)

Descrizione

Descrizione generale

Uteroglobin, also known as clara cell phospholipid-binding protein or CC10, is a member of the secretoglobin superfamily. It is secreted from nonciliated cells in the epithelial lining of bronchioles, also referred as Clara cells.[1][2] Uteroglobin is encoded by the gene mapped to human chromosome 11q12.2 – 13.1.[3] Recombinant Human Uteroglobin is an 8.0kDa homodimeric protein consisting of 142 amino acid residues.

Azioni biochim/fisiol

Uteroglobin functions as an immunomodulatory and anti-inflammatory protein. Uteroglobin might play a vital role in regulation of airway inflammation.[2] Elevated level of uteroglobin has been observed in fallopian tubes of tubal ectopic pregnant women and in female patients with pelvic inflammatory disease.[4] Uteroglobin level is reduced in serum of asthmatic patients with a long duration of the disease.[2] Uteroglobin stimulates the growth of preimplantation blastocysts and it functions as a carrier and/or scavenger of progesterone, decreasing its toxicity to the early developing embryo. Uteroglobin has the capacity to prevent both chemotaxis and phagocytosis of monocytes and neutrophils.[3]

Stato fisico

Lyophilized from 1 x PBS

Ricostituzione

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable