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SML1555

Sigma-Aldrich

MS023 hydrochloride

≥98% (HPLC)

Sinonimo/i:

N1-((4-(4-Isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine hydrochloride, N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine hydrochloride

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5 MG
182,00 €
25 MG
722,00 €

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5 MG
182,00 €
25 MG
722,00 €

About This Item

Formula empirica (notazione di Hill):
C17H25N3O · xHCl
Numero CAS:
Peso molecolare:
287.40 (free base basis)
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

182,00 €


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Livello qualitativo

Saggio

≥98% (HPLC)

Stato

powder

Condizioni di stoccaggio

desiccated

Colore

white to light brown

Solubilità

H2O: 20 mg/mL, clear

Temperatura di conservazione

−20°C

Stringa SMILE

CN(CCN)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2.[H]Cl

InChI

1S/C17H25N3O.ClH/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18;/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3;1H
IEZPALXFXHDDHI-UHFFFAOYSA-N

Azioni biochim/fisiol

MS023 is a potent and selective chemical probe for Type I protein arginine methyltransferases (PRMTs).
MS023 is a potent and selective chemical probe for Type I protein arginine methyltransferases (PRMTs). MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues. MS023 is active in cells. For full characterization details, please visit the MS023 probe summary on the Structural Genomics Consortium (SGC) website.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

Caratteristiche e vantaggi

MS023 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Altre note

MS023 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the MS023 probe summary on the Chemical Probes Portal website.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

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