SML1158

(2S)-Hypusine dihydrochloride

≥95% (HPLC)

• Sinonimo/i: (+)-Hypusine dihydrochloride, N6-[(2RS)-4-Amino-2-hydroxybutyl]-L-lysine dihydrochloride
• Formula empirica (notazione di Hill): C₁₀H₂₃N₃O₃ · 2HCl
• Peso molecolare: 306.23
• Codice UNSPSC: 12352209
• ID PubChem: 329825688
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Forma fisica: powder
• Condizioni di stoccaggio: desiccated
• Colore: white to beige
• Solubilità: H₂O: 15 mg/mL, clear
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H]Cl.[H]Cl.N[C@H](C(O)=O)CCCCNCC(O)CCN
• InChI: 1S/C10H23N3O3.2ClH/c11-5-4-8(14)7-13-6-2-1-3-9(12)10(15)16;;/h8-9,13-14H,1-7,11-12H2,(H,15,16);2*1H/t8?,9-;;/m0../s1; UTSZZUVUESAPQD-AHBBCRTASA-N

Descrizione

Azioni biochim/fisiol

(2S)-Hypusine is an unusual amino acid found only in eukaryotic translation initiation factor 5A (eIF5A) and a similar protein in archaebacteria. (2S)-Hypusine is formed by posttranslational modification of a lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. There is increasing interest in the polyamine-hypusine axis and eIF5A, its a role in cell growth and differentiation, and a recent paper on the polyamine-hypusine axis as a potential new tumour suppressor network.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable