The serotype is OX19.
SMB00801
Lipopolysaccharides from Proteus vulgaris
purified by phenol extraction
Sinonimo/i:
LPS
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238,00 €
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About This Item
Codice UNSPSC:
12352211
NACRES:
NA.28
Prodotti consigliati
Origine biologica
bacterial (Proteus vulgaris)
Livello qualitativo
Stato
lyophilized powder
Purificato mediante
phenol extraction
Impurezze
≤3% Protein (Lowry)
Colore
white to yellow cast
Solubilità
water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
Condizioni di spedizione
ambient
Temperatura di conservazione
2-8°C
Descrizione generale
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. They consist of lipid A moiety linked to an antigenic O-polysaccharide.
Proteus vulgaris is a rod-shaped Gram-negative, facultative anaerobe bacterium. It inhabits the intestinal tract of humans and animals and can be found in soil, water and feces.[1] P. vulgaris is a member of the Enterobacteriaceae family which are opportunistic pathogens in humans, responsible for urinary tract and burn infections.[2]
The chemical structures of LPS from Proteus sp. are different from each other.
Proteus vulgaris is a rod-shaped Gram-negative, facultative anaerobe bacterium. It inhabits the intestinal tract of humans and animals and can be found in soil, water and feces.[1] P. vulgaris is a member of the Enterobacteriaceae family which are opportunistic pathogens in humans, responsible for urinary tract and burn infections.[2]
The chemical structures of LPS from Proteus sp. are different from each other.
Azioni biochim/fisiol
LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular patterns (PAMPs). Different chemical structures of LPS can be associated with the virulence and pathogenesis of the bacteria.[3][4][5] It has been reported that the LPS chemical structure from P. vulgaris can influence the crystallization of mineral urine components (such as calcium and magnesium), resulting in stone formation in the kidney.[6] Antibodies produced in rickettsial infections were found to react with LPS from Proteus vulgaris and Proteus mirabilis. This phenomenon allows the purified LPS from these two species to serve as a tool for the diagnosis of rickettsiosis (scrub typhus, caused by the bacterium Orientia sp.) in the Weil-Felix test.[7]
Altre note
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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D J HOSSACK
British journal of pharmacology and chemotherapy, 19, 306-312 (1962-10-01)
Ascending urinary tract infections with stone formation have been produced experimentally in rats, using a modification of the method of Vermuelen & Goetz (1954a, b). A zinc disc infected with a culture of Proteus vulgaris was inserted into the bladder
A Torzewska et al.
FEMS immunology and medical microbiology, 31(3), 227-234 (2001-11-27)
The O-specific polysaccharide (O-antigen) of the lipopolysaccharide (LPS) of Proteus vulgaris O37 was studied by (1)H and (13)C nuclear magnetic resonance spectroscopy before and after O-deacetylation and found to be structurally similar to that of P. vulgaris O46 studied earlier.
S Mizushiri et al.
Microbiology and immunology, 34(2), 121-133 (1990-01-01)
The lipopolysaccharides (LPS) extracted from Proteus strains OX2, OX19, and OXK used as antigens in the Weil-Felix test, were characterized by chemical analysis and SDS-polyacrylamide gel electrophoresis (SDS-PAGE). To separate the O-polysaccharide, core-oligosaccharide, and lipid A moieties, each LPS was
LPS/TLR4 signal transduction pathway
Lu, Y.C., Yeh, W.C., Ohashi, P.S.
Cytokine, 42, 145-151 (2008)
Generation and characterization of a lipopolysaccharide-specific murine monoclonal antibody to Proteus vulgaris OX19
Bakshi, D., Jain, R., Tuteja, U., Batra, H.V.
World Journal of Microbiology & Biotechnology, 23, 817-821 (2007)
Articoli
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
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What is the serotype of Proteus vulgaris used for this LPS?
1 risposta-
Utile?
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Which O-antigen does that P.vulgaris come with? And from which strain was the LPS isolated?
1 risposta-
The o-antigen is O-polysaccharide. The strain is considered proprietary. Please see the link below for additional information that may be helpful.
https://pubmed.ncbi.nlm.nih.gov/9858461/The link below offers additional information to all of the lectin products, as well as a helpful selection guide:
https://www.sigmaaldrich.com/technical-documents/technical-article/research-and-disease-areas/glycobiology/lectin-selection-guide-useful-guide-for-selecting-right-lectin#lectinUtile?
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