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SAB4700767

Sigma-Aldrich

Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

clone HB5, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Hbsag Antibody, Hbsag Antibody - Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

HB5, monoclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

hepatitis B virus

Concentrazione

1 mg/mL

tecniche

ELISA: suitable
immunocytochemistry: suitable

Isotipo

IgG2a

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Descrizione generale

HBsAg is the surface antigen of HBV (hepatitis B virus). It is secreted in the form of pleomorphic particles, mostly spherical and partly filamentous. HBV is usually spread due to percutaneous or mucosal exposure to infected blood and other body fluids.
The antibody HB5 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.

Immunogeno

Purified HbsAg from human plasma.

Applicazioni

Monoclonal Anti-HBV antigen HBsAg antibody has been used in quantitative assays.

Azioni biochim/fisiol

HBsAg acts as a clinical marker and helps to specify acute or chronic infection. Presence of HBsAg indicates HBV infection. Overexpression of HBsAg is seen in infected hepatocytes.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Palashpriya Das et al.
World journal of hepatology, 12(10), 775-791 (2020-11-18)
The recent rise in the incidence of hepatitis B virus (HBV) infections in a densely populated city of eastern India ("mixing vessel" of people of varied socio-economic and immune status) prompted this study. Applying saliva on fingers for enumerating bank
Establishment of magnetic microparticles-assisted time-resolved fluoroimmunoassay for determinating biomarker models in human serum.
Ren ZQ, et al.
PLoS ONE, 10(6), e0130481-e0130481 (2015)
Abinash Mallick et al.
Journal of medical virology, 96(6), e29771-e29771 (2024-06-27)
COVID-19 tended to be less aggressive in dengue endemic regions. Conversely, dengue cases plummeted in dengue endemic zones during the active years of the pandemic (2020-2021). We and others have demonstrated serological cross-reactivity between these two viruses of different families.
Yunru Chen et al.
Journal of medical virology, 91(10), 1811-1817 (2019-06-19)
The safety and necessity of hepatitis B immunoglobulin (HBIG) in preventing the mother-to-child transmission of hepatitis B virus (HBV) are still controversial because of its unclear mechanism of action and the inconsistent injection programs used during gestation. This study aimed
Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity.
Ott JJ, et al.
Vaccine, 30(12), 2212-2219 (2012)

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