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S5261

Sigma-Aldrich

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

Sinonimo/i:

Selenious acid, Sodium salt

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About This Item

Formula condensata:
Na2SeO3
Numero CAS:
Peso molecolare:
172.94
Numero CE:
Numero MDL:
Codice UNSPSC:
12352205
ID PubChem:
NACRES:
NA.75

Origine biologica

synthetic (inorganic)

Nome Commerciale

BioReagent

Saggio

≥98%

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Punto di fusione

>350 °C (lit.)

Solubilità

water: 50 mg/mL, clear to very slightly hazy, colorless

Stringa SMILE

[Na+].[Na+].[O-][Se]([O-])=O

InChI

1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
BVTBRVFYZUCAKH-UHFFFAOYSA-L

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Applicazioni

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Pittogrammi

Skull and crossbonesEnvironment

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Rischi supp

Codice della classe di stoccaggio

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Certificati d'analisi (COA)

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Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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