If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf
A8960
2-fosfato di acido L-ascorbico
≥95%
Sinonimo/i:
MAP, Magnesio ascorbil fosfato
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About This Item
Prodotti consigliati
Origine biologica
synthetic (organic)
Saggio
≥95%
Stato
powder
tecniche
HPLC: suitable
Colore
white to off-white
Solubilità
water: 50 mg/mL
Temperatura di conservazione
room temp
Stringa SMILE
O=C1O[C@@]([C@@H](O)CO)([H])C([O-])=C1OP([O-])([O-])=O.O=C2O[C@@]([C@@H](O)CO)([H])C([O-])=C2OP([O-])([O-])=O.O.[Mg+2].[Mg+2].[Mg+2]
InChI
1S/2C6H9O9P.3Mg.H2O/c2*7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;;/h2*2,4,7-9H,1H2,(H2,11,12,13);;;;1H2/q;;3*+2;/p-6/t2*2-,4+;;;;/m00..../s1
HKRNHMZODRSAPN-IXNKEUJHSA-H
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Categorie correlate
Descrizione generale
Inoltre il MAP svolge un ruolo centrale nella ricerca sulla metabolomica e in ambito biochimico. In virtù della sua azione antiossidante, interviene come efficace scavenger di radicali liberi proteggendo così le cellule dal danno ossidativo. Le sue proprietà anti-infiammatorie contribuiscono a ridurre l′infiammazione e alcuni studi hanno evidenziato la sua capacità di stimolare la produzione di collagene. Oltre a questo, il MAP può essere impiegato come agente di chelazione, e il suo impiego può quindi estendersi ad altri ambiti di ricerca. La natura poliedrica del MAP ne fa uno strumento apprezzato nell′ambito delle indagini scientifiche, in grado di contribuire ai progressi della ricerca in campi come la biologia cellulare, la metabolomica e la biochimica.
Applicazioni
Azioni biochim/fisiol
Caratteristiche e vantaggi
- Può essere impiegato in attività di ricerca in biologia cellulare, metabolomica e in biochimica
- Composto di qualità elevata indicato per un′ampia varietà di applicazioni di ricerca
Altre note
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Certificati d'analisi (COA)
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How can I determine the shelf life / expiration / retest date of this product?
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Utile?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Utile?
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How long is stable at -20 or -80 degrees, if dissolved in water or media? By any chance, did you tested the stability of this product at -20 °C or -80 °C?
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Unfortunately, the solution stability of this product at freezer temperatures has not been determined. This product is soluble in water at 50 mg/ml. Stock solutions have been found to retain 85% activity for 1 week at 37 °C and 80% activity for 1 month at refrigerated temperatures.
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To whom it may concern, I would like to know more on the biocompatibility of L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate. Could you please send me an example of certificate of analysis for this compound? Thanks a lot. S. Chatellier
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Please see the link below to access a specific lot or review a sample Certificate:
https://www.sigmaaldrich.com/product/sigma/A8960#product-documentationUtile?
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What type of filter membrane can be used to sterilize ascorbic acid?
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After reconstitution in water, it is recommended to sterilize the solution using a 0.22 micron PES filter, such as one of the following products, or any other dimension that better fits the end user's needs.
https://www.sigmaaldrich.com/substance/steritopthreadedbottletopfilter1234598765Utile?
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Is A8960 sterile? or can i find a sterile alternative?
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This is not a sterile product. Stock solutions should be filter-sterilized. The compound is soluble in water at 50 mg/mL. The solution stability has not been determined.
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What is the shelf life/stability since purchased? In powder condition in its original container, at room temperature
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This product does not contain an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
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Can stock solutions of this compound be frozen and retain their activity for extended periods of time?
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The product stability has not been determined in freezer temperature. Stock solutions that are stored at 5 °C are approximately 80% active after 4 weeks.
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How long is A8960 stable in water when frozen at -20C?
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This product stability has not been determined in freezer temperature. Stocks solutions that are stored at 5 °C are approximately 80% active after 4 weeks.
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How long is stable at -20 or -80 degrees, if dissolved in water or media ? Thinking to prepare a stock solution. Thank you
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This product is soluble in water at 50 mg/ml, forming a clear colorless to yellow solution. Stocks solutions that are stored at 5 °C are approximately 80% active after 4 weeks.
If this product is reconstituted or diluted into media, it retains approximately 85% of its activity after 1 week at 37 °C and approximately 80% for 1 month at 5 °C.
This product stability has not been determined at -20 °C or -80 °C.
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