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P7903

Sigma-Aldrich

Pipemidic acid

Sinonimo/i:

8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid

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About This Item

Formula empirica (notazione di Hill):
C14H17N5O3
Numero CAS:
51940-44-4
Peso molecolare:
303.32
Numero CE:
257-530-2
Numero MDL:
MFCD00057291
Codice UNSPSC:
51282938
ID PubChem:
24898889
NACRES:
NA.85

Forma fisica

powder

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria

Modalità d’azione

DNA synthesis | interferes
cell wall synthesis | interferes
enzyme | inhibits

Stringa SMILE

CCN1C=C(C(O)=O)C(=O)c2cnc(nc12)N3CCNCC3

InChI

1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22)
JOHZPMXAZQZXHR-UHFFFAOYSA-N

Informazioni sul gene

human ... CYP1A2(1544)

Descrizione generale

Chemical structure: quinolone

Applicazioni

Pipemidic acid is used to study DNA damage and mutagenic activity. It has been used to induce articular lesions in the neonatal mouse and is used to study human lymphocyte blastogenesis and γ-interferon production .

Azioni biochim/fisiol

Pipemidic acid modulates (inhibits) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation. Pipemidic acid has been shown to induce inhibition of lymphocyte DNA synthesis.

Risultati analitici

Very slightly soluble in water. It dissolves in diluted solutions of acids and of alkali hydroxides.

Altre note

10g,100g
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H317,H334

Classi di pericolo

Resp. Sens. 1 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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