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P0094

Sigma-Aldrich

Perindopril erbumine

Sinonimo/i:

(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt, S-9490

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50 MG
199,00 €
250 MG
781,00 €

199,00 €

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Cambia visualizzazione
50 MG
199,00 €
250 MG
781,00 €

About This Item

Formula empirica (notazione di Hill):
C19H32N2O5 · C4H11N
Numero CAS:
107133-36-8
Peso molecolare:
441.60
Numero MDL:
MFCD02313824
Codice UNSPSC:
12352200
ID PubChem:
329820011
NACRES:
NA.77

199,00 €

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Saggio

≥98% (HPLC)

Stato

powder

Solubilità

H2O: 10 mg/mL, clear

Ideatore

Xoma

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC

InChI

1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1
IYNMDWMQHSMDDE-MHXJNQAMSA-N

Informazioni sul gene

human ... ACE(1636)

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Azioni biochim/fisiol

Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive.
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke.

Caratteristiche e vantaggi

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Xoma. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Health hazard
GHS08

Avvertenze

Warning

Indicazioni di pericolo

H361d

Classi di pericolo

Repr. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
0000180727
0000180726
0000193600
014M4701V
062M4747V

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