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N7251

Sigma-Aldrich

4-Nitrocatechol sulfate dipotassium salt

crystalline

Sinonimo/i:

2-Hydroxy-5-nitrophenyl sulfate, 2-Hydroxy-5-nitrophenyl sulfate dipotassium salt monohydrate, p-Nitrocatechol sulfate dipotassium salt

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About This Item

Formula condensata:
C6H3NO7SK2
Numero CAS:
14528-64-4
Peso molecolare:
311.35
Beilstein:
3805018
Numero CE:
238-550-0
Numero MDL:
MFCD00007465
Codice UNSPSC:
12352200
ID PubChem:
24897816
NACRES:
NA.77

Forma fisica

crystalline

Colore

yellow

Temperatura di conservazione

−20°C

Stringa SMILE

[K+].[K+].[O-]c1ccc(cc1OS([O-])(=O)=O)[N+]([O-])=O

InChI

1S/C6H5NO7S.2K/c8-5-2-1-4(7(9)10)3-6(5)14-15(11,12)13;;/h1-3,8H,(H,11,12,13);;/q;2*+1/p-2
CKWWBDCAYRJAJB-UHFFFAOYSA-L

Descrizione generale

4-Nitrocatechol sulfate is an aromatic sulfate.

Applicazioni

4-Nitrocatechol sulfate dipotassium salt has been used as a substrate in mucopolysaccharidoses VI (MPS VI) analysis. It has also been used to measure the activity of glycosaminoglycan (GAG)-degrading enzymes-arylsulfatase B, and exoglycosidases.

Substrati

Chromogenic sulfatase substrate.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Jin-Peng Sun et al.
The Journal of biological chemistry, 278(35), 33392-33399 (2003-06-18)
The pathogenic bacteria Yersinia are causative agents in human diseases ranging from gastrointestinal syndromes to bubonic plague. There is increasing risk of misuse of infectious agents, such as Yersinia pestis, as weapons of terror as well as instruments of warfare
The convulsive effects of dopamine sulfate conjugates in rat brain.
N T Buu et al.
Life sciences, 29(22), 2311-2316 (1981-11-30)
D B Thompson et al.
Experientia, 42(2), 150-151 (1986-02-15)
Rodent and bovine arylsulfatase B hydrolyze 4-methylumbelliferyl sulfate (4MUS) 10- to 30-fold more efficiently than arylsulfatase A. Therefore, 4MUS grossly underestimates arylsulfatase A activity in the presence of excess arylsulfatase B.
P L Chang et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 32(6), 617-624 (1984-06-01)
A staining reaction was developed to specifically detect arylsulfatase A activity in the presence of arylsulfatases B and C. Nitrocatechol, generated by all arylsulfatases from the substrate p-nitrocatechol sulfate, can be coupled to produce Hatchett 's brown which reacts with
Ilhem Barboura et al.
Diagnostic pathology, 7, 11-11 (2012-01-31)
Metachromatic leukodystrophy (MLD) is a recessive autosomal disease which is characterized by an accumulation of sulfatides in the central and peripheral nervous system. It is due to the enzyme deficiency of the sulfatide sulfatase i.e. arylsulfatase A (ASA). we studied
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