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M9771

Sigma-Aldrich

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin

elastase substrate

Sinonimo/i:

MeOSuc-AAPV-AMC

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About This Item

Formula empirica (notazione di Hill):
C31H41N5O9
Numero CAS:
72252-90-5
Peso molecolare:
627.69
Numero MDL:
MFCD00077135
Codice UNSPSC:
12352204
ID PubChem:
24897367
NACRES:
NA.32

Saggio

≥98% (HPLC)

Forma fisica

powder

Solubilità

chloroform: 50 mg/mL, clear, colorless

Temperatura di conservazione

−20°C

Stringa SMILE

COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)
CMEUDEVBFFPSEI-UHFFFAOYSA-N

Applicazioni

N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin has been used as a substrate in elastase assay using bone marrow lysates and pancreatic lysates.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrati

Fluorogenic substrate for the assay of human leukocyte and porcine pancreatic elastase.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(1), 1401-1414 (2018-08-22)
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Sensitive substrates for human leukocyte and porcine pancreatic elastase: a study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases.
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Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.

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