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L4127

Sigma-Aldrich

DL-Leu-Gly-Gly

≥99% (TLC), suitable for ligand binding assays

Sinonimo/i:

DL-leucylglycylglycine

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About This Item

Formula empirica (notazione di Hill):
C10H19N3O4
Numero CAS:
4337-37-5
Peso molecolare:
245.28
Numero CE:
224-384-6
Numero MDL:
MFCD00064990
Codice UNSPSC:
12352202
ID PubChem:
24896362
NACRES:
NA.26

product name

DL-Leu-Gly-Gly,

Saggio

≥99% (TLC)

Forma fisica

powder

tecniche

ligand binding assay: suitable

Colore

white to off-white

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)CC(N)C(=O)NCC(=O)NCC(O)=O

InChI

1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)
VWHGTYCRDRBSFI-UHFFFAOYSA-N

Amino Acid Sequence

Leu-Gly-Gly

Azioni biochim/fisiol

Leucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinase (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidase (EC 3.4.11.4) and other peptidase(s) such as leucylglycylglycine aminopeptidase (EC 3.4.1.3).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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L C Masek et al.
Experimental hematology, 22(12), 1203-1209 (1994-11-01)
"Homing" of hematopoietic progenitor cells to the bone marrow occurs during the clinical practice of bone marrow transplantation. Its mechanism is unknown, although adhesive interactions between hematopoietic cells and sinusoidal endothelium in the bone marrow may be implicated. Studies of
María B Espeche Turbay et al.
Journal of agricultural and food chemistry, 57(18), 8607-8611 (2009-09-17)
The cell-envelope-associated proteinase of Lactobacillus delbrueckii subsp. lactis CRL 581 (PrtL) has an essential role in bacterial growth and contributes to the development of the organoleptic properties of hard cheeses and to the release of bioactive health-beneficial peptides from milk
G F Vaeth et al.
Journal of pediatric gastroenterology and nutrition, 1(1), 111-117 (1982-01-01)
The development and distribution of peptidase activity in mucosal homogenates of rat small intestine has been investigated. Substrates used were glycyl-L-leucine (GL), L-seryl-L-methionine (SM), and L-leucyl-glycyl-glycine (LGG). During the first 2 weeks of life there was high peptidase activity toward
S Kanda et al.
Clinical chemistry, 30(6), 843-846 (1984-06-01)
This is a method for measuring tripeptide aminopeptidase (EC 3.4.11.4) activity in serum. L- Leucylglycylglycine is used as substrate, and the reaction is followed by monitoring the absorbance increase at 340 nm when NAD+ is reduced to NADH in the
Qiqin Wang et al.
Journal of chromatography. A, 1428, 176-184 (2015-09-28)
In the present study, a new analytical methodology was developed enabling the enantiomeric determination of N-derivatized di- and tri-peptides in dietary supplements using chiral micro-LC on a monolithic column consisting of poly(O-9-[2-(methacryloyloxy)-ethylcarbamoyl]-10,11-dihydroquinidine-co-2-hydroxyethyl methacrylate-co-ethylene dimethacrylate) (poly(MQD-co-HEMA-co-EDMA)). After optimization of the mobile
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