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H0267

Sigma-Aldrich

Hemoglobin A0, Ferrous Stabilized human

lyophilized powder

Sinonimo/i:

Hemoglobin A0 Ferrous Stabilized, Hemoglobin-A0

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About This Item

Numero CAS:
54651-57-9
Numero CE:
259-278-9
Numero MDL:
MFCD00131287
Codice UNSPSC:
12352202
eCl@ss:
42030116
NACRES:
NA.61

Origine biologica

human

Livello qualitativo

200

Saggio

97-100% (agarose gel electrophoresis)

Forma fisica

lyophilized powder

tecniche

immunofluorescence: suitable

Solubilità

H2O: soluble 20 mg/mL

Compatibilità

suitable for electrophoresis and chromatography standard

N° accesso UniProt

P68871

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... HBB(3043)

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Descrizione generale

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).

Applicazioni

Hemoglobin A0, ferrous stabilized human has been used:
  • as the non-fluorescent absorber in the preparation of tissue-mimicking phantoms
  • to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype
  • to study the interference of hemoglobin (Hb) A0, HbA2, and HbS in the assay of HbF

Hemoglobin A0 was used to see how coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. It was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.

Azioni biochim/fisiol

Variation in the haemoglobin (Hb) encoding genes results in haemoglobinopathies such as thalassaemia and atypical structural variants like Hb Lepore and HbE.

Confezionamento

Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).

Ricostituzione

When reconstituted with buffer, gives >85% ferrous hemoglobin.

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Seung Yup Lee et al.
Science advances, 6(47) (2020-11-22)
Pancreatic cancer is one of the deadliest cancers, with a 5-year survival rate of <10%. The current approach to confirming a tissue diagnosis, endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), requires a time-consuming, qualitative cytology analysis and may be limited because of
Vivide Tuan-Chyan Chang et al.
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Cervical cancer is the second most common female cancer worldwide. The ability to quantify physiological and morphological changes in the cervix is not only useful in the diagnosis of cervical precancers but also important in aiding the design of cost-effective
Screening and diagnosis for haemoglobin disorders
Prevention of Thalassaemias and Other Haemoglobin Disorders, 1 (2013)
Motasam Majedy et al.
Journal of biomedical optics, 27(7) (2021-12-02)
For optical methods to accurately assess hemoglobin oxygen saturation in vivo, an independently verifiable tissue-like standard is required for validation. For this purpose, we propose three hemoglobin preparations and evaluate methods to characterize them. To spectrally characterize three different hemoglobin
Randi E Gislefoss et al.
Biopreservation and biobanking, 19(6), 525-530 (2021-10-07)
Background: During sampling and processing, blood samples can be affected by hemolysis. Information is lacking regarding hemolysis for biobank samples. There is a need for a method that can easily measure hemoglobin as an indicator of hemolysis in stored samples
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