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Documenti fondamentali

D6898

Sigma-Aldrich

Deoxyribonucleic acid sodium salt from herring testes

Type XIV

Sinonimo/i:

DNA

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
41106305
eCl@ss:
32160414
NACRES:
NA.51

Tipo

Type XIV

Livello qualitativo

Stato

solid

Temperatura di conservazione

2-8°C

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Descrizione generale

Deoxyribonucleic acid sodium salt from herring testes, also known as HtDNA is a natural source of DNA designed for DNA binding agent studies. The detection limits of HtDNA are around 5.0ng and linear ranges of light scattering intensity (I(LS)) is 0.05-2.5 mµg.

Applicazioni

Deoxyribonucleic acid sodium salt from herring testes is used in studies of DNA binding agents that modulate DNA structure and function. Herring testes DNA is also used in physicochemical studies of DNA behavior in solution.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Assaf Marcus et al.
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
X Du et al.
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
Larisa I Labzin et al.
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
Renée M Van der Sluis et al.
PLoS pathogens, 16(2), e1008151-e1008151 (2020-02-29)
HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells do not
K L Jønsson et al.
Nature communications, 8, 14391-14391 (2017-02-12)
Innate immune activation by macrophages is an essential part of host defence against infection. Cytosolic recognition of microbial DNA in macrophages leads to induction of interferons and cytokines through activation of cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes

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