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D5412

Sigma-Aldrich

2′-Deoxyuridine

≥98.5%

Sinonimo/i:

1-(2-Deoxy-β-D-ribofuranosyl)uracil, Uracil deoxyriboside

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About This Item

Formula empirica (notazione di Hill):
C9H12N2O5
Numero CAS:
951-78-0
Peso molecolare:
228.20
Beilstein:
24433
Numero CE:
213-455-7
Numero MDL:
MFCD00006527
Codice UNSPSC:
41106305
ID PubChem:
24893831
NACRES:
NA.51

Origine biologica

synthetic (organic)

Saggio

≥98.5%

Forma fisica

powder

Impurezze

Thymidine, free

Solubilità

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

Stringa SMILE

OC[C@H]1O[C@H](C[C@@H]1O)N2C=CC(=O)NC2=O

InChI

1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1
MXHRCPNRJAMMIM-SHYZEUOFSA-N

Informazioni sul gene

mouse ... Slc29a1(63959)

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Categorie correlate

Applicazioni

2′-Deoxyuridine has been used as a:
  • precursor of [3H]thymidine triphosphate (TTP) in place of thymidine to avoid a potential thymidine block in relative proliferation assays
  • nucleoside supplement for cell cycle synchronization and DNA replication inhibition
  • mitotic inhibitor in culture media to minimize the proliferation of glial cells

Azioni biochim/fisiol

2′-Deoxyuridine (dU) is frequently halogenated to create thymidine analogs useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-deoxyuridines used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogs of 2′-deoxyuridine include 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

D7400

2′-Deoxyadenosine monohydrate

Timidina ≥99%

Sigma-Aldrich

T9250

Timidina

3-Ureidopropionic acid ≥98.0% (T)

Sigma-Aldrich

94295

3-Ureidopropionic acid

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Sigma-Aldrich

900584

5-Ethynyl-2′-deoxyuridine

Uridine powder, BioReagent, suitable for cell culture

Sigma-Aldrich

U3003

Uridine

Uridine ≥99%

Sigma-Aldrich

U3750

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α-Thymidine

Sigma-Aldrich

T3763

α-Thymidine

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