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Documenti fondamentali

B1422

Sigma-Aldrich

B-Trisaccharide

Sinonimo/i:

α-D-Gal-(1→3)-(α-L-Fuc-[1→2])-D-Gal, Blood group B trisaccharide

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About This Item

Formula empirica (notazione di Hill):
C18H32O15
Numero CAS:
Peso molecolare:
488.44
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:

Saggio

≥95% (H-NMR)

Livello qualitativo

Stato

solid

Temperatura di conservazione

2-8°C

Stringa SMILE

C[C@@H]1O[C@@H](O[C@H]2C(O)O[C@H](CO)[C@H](O)[C@@H]2O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C18H32O15/c1-4-7(21)10(24)12(26)17(29-4)33-15-14(9(23)6(3-20)30-16(15)28)32-18-13(27)11(25)8(22)5(2-19)31-18/h4-28H,2-3H2,1H3/t4-,5+,6+,7+,8-,9-,10+,11-,12-,13+,14-,15+,16?,17-,18+/m0/s1
XNBZPOHDTUWNMW-OUUCXATCSA-N

Applicazioni

Blood group B trisaccharide may be used to isolate, identify and characterize blood group trisaccharide specific lectins and ligands such as Langerin and MOA (Marasmius oreades agglutinin).[1][2]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Elin M Grahn et al.
Journal of molecular biology, 390(3), 457-466 (2009-05-12)
MOA (Marasmius oreades agglutinin), a lectin isolated from fruiting bodies of the mushroom M. oreades, specifically binds nonreducing terminal Galalpha(1,3)Gal carbohydrates, such as that which occurs in the xenotransplantation epitope Galalpha(1,3)Galbeta(1,4)GlcNAc and the branched blood group B determinant Galalpha(1,3)[Fucalpha(1,2)]Gal. Here
N O Seto et al.
European journal of biochemistry, 234(1), 323-328 (1995-11-15)
A 1034-bp synthetic gene encoding the human blood group B glycosyltransferase, which catalyzes the transfer of galactose from UDP-Gal to Fuc alpha(1-2)Gal beta-OR to give the blood group B determinant Gal alpha(1-3)[Fuc alpha(1-2)]Gal beta-OR (where R is a glycoprotein or
L Rydberg et al.
Sub-cellular biochemistry, 32, 107-125 (1999-07-07)
alpha-Gal terminated saccharides are present on the cell surface both as glycolipids and glycoproteins in all mammals except Old World monkeys and humans. The structural diversity among identified saccharides terminated by this epitope in animal tissues is steadily increasing. The
Brian P Rempel et al.
Glycoconjugate journal, 19(3), 175-180 (2003-06-20)
A novel lectin from the mushroom Marasmius oreades (MOA) has been shown to bind to human blood group B oligosaccharides [1]. In the present work we examine the binding of a series of analogues of the blood group B-trisaccharide, alphaGal(1-3)[alphaFuc(1-2)]betaGal-OR
Ming Tan et al.
PloS one, 4(4), e5058-e5058 (2009-04-02)
Human noroviruses are the major viral pathogens of epidemic acute gastroenteritis. These genetically diverse viruses comprise two major genogroups (GI and GII) and approximately 30 genotypes. Noroviruses recognize human histo-blood group antigens (HBGAs) in a diverse, strain-specific manner. Recently the

Articoli

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

Domande

Recensioni

Nessuna valutazione

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