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A0262

Sigma-Aldrich

Lithium potassium acetyl phosphate

≥85% (elemental analysis), powder

Sinonimo/i:

Acetyl phosphate lithium potassium salt

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500 MG
153,00 €
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Cambia visualizzazione
500 MG
153,00 €
1 G
254,00 €
5 G
550,00 €

About This Item

Formula condensata:
CH3COOP(O)(OK)(OLi)
Numero CAS:
Peso molecolare:
184.06
Beilstein:
5689718
Numero CE:
Numero MDL:
Codice UNSPSC:
12352204
ID PubChem:
NACRES:
NA.32

153,00 €


Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Nome del prodotto

Lithium potassium acetyl phosphate, high-energy phosphate donor

Saggio

≥85% (elemental analysis)

Stato

powder

Punto di fusione

>300 °C (lit.)

Solubilità

water: 25 mg/mL, clear, colorless

Temperatura di conservazione

−20°C

Stringa SMILE

[Li+].[K+].CC(=O)OP([O-])([O-])=O

InChI

1S/C2H5O5P.K.Li/c1-2(3)7-8(4,5)6;;/h1H3,(H2,4,5,6);;/q;2*+1/p-2
RLQMPLKXFIXRCV-UHFFFAOYSA-L

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Categorie correlate

Applicazioni

Lithium potassium acetyl phosphate:
  • has been used as a substrate for CpxR (transcription factor) in x-ray crystallography to soak CpxR receiver domain (CpxRRD) crystals to obtain the phosphorylated form[1]
  • may be used as a phosphate (P) donor in a study to screen a wide range of natural and synthetic organic phosphate donors with several enzymes on various hydroxyl?compounds for the improved enzymatic synthesis of phosphate monoesters[2]
  • has been used to set up premixA for in vitro translation reaction[3]

Azioni biochim/fisiol

Lithium potassium acetyl phosphate is commonly used as the source for acetyl phosphate. So acetyl phosphate can be used as a suitable alternative to replace inorganic oligophosphates in phosphatase-catalyzed transphosphorylation to reduce inorganic monophosphate by-product formation.[2]

Pittogrammi

Health hazardCorrosion

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Codice della classe di stoccaggio

8B - Non-combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Soma Mukhopadhyay et al.
Bioorganic chemistry, 36(2), 65-69 (2008-02-26)
Acetate kinase, a member of the ASKHA (Acetate and Sugar Kinases, Hsp70, Actin) phosphotransferase superfamily is a central enzyme in prokaryotic carbon and energy metabolism. Recently extensive structural and biochemical studies of acetate kinase and related carboxylate kinases have been
Gábor Tasnádi et al.
Advanced synthesis & catalysis, 360(12), 2394-2401 (2018-10-20)
Undesired product hydrolysis along with large amounts of waste in form of inorganic monophosphate by-product are the main obstacles associated with the use of pyrophosphate in the phosphatase-catalyzed synthesis of phosphate monoesters on large scale. In order to overcome both
Ariel E Mechaly et al.
Structure (London, England : 1993), 25(6), 939-944 (2017-05-30)
Bacterial two-component systems consist of a sensor histidine kinase (HK) and a response regulator (RR). HKs are homodimers that catalyze the autophosphorylation of a histidine residue and the subsequent phosphoryl transfer to its RR partner, triggering an adaptive response. How
Juan Andres Imelio et al.
Bio-protocol, 7(16), e2510-e2510 (2017-08-20)
We have developed protocols to generate site-specific variants of the histidine-kinase DesK and its cognate response regulator DesR, conducive to trapping different signaling states of the proteins. Co-expression of both partners in E. coli, ensuring an excess of the regulator
Sebastian R Schmidl et al.
Nature chemical biology, 15(7), 690-698 (2019-05-22)
Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways and valuable sensors for synthetic biology. However, most TCSs remain uncharacterized or difficult to harness for applications. Major challenges are that many TCS output promoters are unknown, subject

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