Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

95144

Sigma-Aldrich

Retinolo

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

Sinonimo/i:

tutto trans-3,7-dimetil-9-(2,6,6-trimetil-1-cicloesen-1-il)-2,4,6,8-nonatetraen-1-olo, Alcol della vitamina A, Axeroftolo, Vitamina A, Vitamina A1

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali

Scegli un formato

250 MG
137,00 €
1 G
438,00 €

137,00 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk
Tutte le immagini(1)

Scegli un formato

Cambia visualizzazione
250 MG
137,00 €
1 G
438,00 €

About This Item

Formula empirica (notazione di Hill):
C20H30O
Numero CAS:
68-26-8
Peso molecolare:
286.45
Beilstein:
403040
Numero CE:
200-683-7
Numero MDL:
MFCD00001552
Codice UNSPSC:
12352205
eCl@ss:
34058018
ID PubChem:
57653654
NACRES:
NA.28

137,00 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk

Origine biologica

synthetic

Nome Commerciale

BioXtra

Saggio

≥97.5% (HPLC)

Stato

(Powder or Powder with Lumps)

Attività specifica

~3100 U/mg

Durata

limited shelf life

Colore

faint yellow to very dark yellow

Punto di fusione

56-61 °C
61-63 °C (lit.)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Descrizione generale

Retinol or vitamin A alcohol is the main circulating form of vitamin A.[1]

Applicazioni

Retinol has been used:
  • as a standard in peak identification and quantification in reverse phase HPLC[2]
  • as a standard to estimate the concentration of vitamin A[3]
  • to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells[4]
  • as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay[5]

Azioni biochim/fisiol

It is not biologically active and works as a precursor of active retinoids. Retinol is converted to retinaldehyde and subsequently to retinoic acid.[1]
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinol is biological active in a wide range of processes.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Definizione di unità

1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H317,H319,H360FD,H413

Classi di pericolo

Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCL8551
BCCM6917
0000393018
0000393018
BCCM5486

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 7

1 of 7

Vitamin A water-miscible 1 ml = 200,000 I.U. for oral use, EMPROVE® ESSENTIAL, Ph. Eur., BP

SAFC

5.00849

Vitamin A

Retinyl palmitate Type IV, ~1,800,000 USP units/g, oil

Sigma-Aldrich

R3375

Retinyl palmitate

Retinyl propionate ≥98.0% (sum of isomers, HPLC), ~2500 U/mg

Sigma-Aldrich

87809

Retinyl propionate

vibrant-m

R0290000

Retinol esters

9-cis-Retinal vitamin A analog

Sigma-Aldrich

R5754

9-cis-Retinal

Retinil acetato analytical standard

Supelco

46958

Retinil acetato

Retinil acetato BioReagent, suitable for cell culture

Sigma-Aldrich

R0635

Retinil acetato

Understanding the physiological role of retinol-binding protein in vitamin A metabolism using transgenic and knockout mouse models
Quadro L, et al.
Molecular Aspects of Medicine, 24(6), 421-430 (2003)
Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome
Lee H and Ko G
Scientific reports, 25835-25835 (2016)
Retinyl palmitate does not have an adjuvant effect on the antibody response of chicks to keyhole limpet hemocyanin regardless of vitamin A status
Livingston KA and Klasing KC
Poultry Science, 90(5), 965-970 (2011)
Heetae Lee et al.
Scientific reports, 6, 25835-25835 (2016-05-18)
The effect and underlying mechanism of vitamin A on norovirus infection are largely unknown. This study aimed to investigate how vitamin A administration affects the gut microbiome after norovirus infection. Here, we demonstrate that treatment with either retinol or retinoic
Responses of blood metabolites and proteins to different vitamin A levels in Korean native steers.
Wang T, et al.
Pakistan journal of botany, 34(4) (2014)
Visualizza tutti i documenti correlati

Protocolli

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Domande

1–2 di 2 domande  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

Recensioni

Nessuna valutazione

Filtri attivi

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.