Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

76546

Sigma-Aldrich

Lipase, immobilized on Immobead 150

≥3000 U/g

Sinonimo/i:

Immobilized lipase, Lipase enzyme

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Codice UNSPSC:
12352204
NACRES:
NA.54

Origine biologica

fungus (Thermomyces lanuginosus)

Livello qualitativo

100

Stato

powder (or beads)

Attività specifica

≥3000 U/g

tecniche

analytical sample preparation: suitable

Colore

white to off-white

applicazioni

life science and biopharma

Temperatura di conservazione

2-8°C

Descrizione generale

Research area: Cell Signaling

Lipase from Thermomyces lanuginosus (TLL) is a basophilic, single-chain protein and thermostable enzyme. It belongs to the alpha/beta-hydrolase fold family. TLL is roughly spherical and is made up of a central seven-stranded β-parallel sheet with five interconnecting α-helices.

Applicazioni

Lipase, immobilized on Immobead 150 from Thermomyces lanuginosus has been used:
  • as a biocatalyst to study ultrasound-assisted transesterification of a blend of non-edible oils with methanol.
  • as a catalyst in the synthesis of medium chain fatty acids (MCFA) and polyunsaturated fatty acids (PUFA) rich oils by enzymatic structuring of flax seed oil.
  • for the resolution of chiral compounds and the transesterification production of biodiesel.
  • to enhance the efficiency and selectivity of the enzymatic synthesis of ethyl-(R)-2-hydroxy-4-phenylbutyrate, (R)-HPB ester.
  • to facilitate a chemoenzymatic process for the continuous synthesis of (S)-7-((tert-Butyldiphenylsilyl)oxy)hept-1-yn-4-ol, a crucial intermediate for Eribulin synthesis, within a packed-bed reactor setup.

Azioni biochim/fisiol

It participates in catalyzing the hydrolysis of triglycerides at the water-lipid interface and produces mono-, di-glycerides, and free fatty acids. Due to its versatility, this enzyme is applicable in various industries including, detergents, paper, leather, baking, fine chemicals, fuel, and biocatalysts.
Lipases catalyze the hydrolysis of triacylglycerols into glycerol and free fatty acids.

Definizione di unità

1 U corresponds to the amount of enzyme which liberates 1 μmol butyric acid per minute at pH 7.5 and 40°C (tributyrin, Cat. No. 91010, as substrate)

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCL5446
BCCK1317
BCCG5229
BCCC2239
BCBV6722

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Study of Thermomyces lanuginosa Lipase in the Presence of Tributyrylglycerol and Water
Santini S, et al.
Biophysical Journal, 96(12), 4814?4825-4814?4825 (2009)
Chemoenzymatic Process for the Preparation of (S)-7-((tert-Butyldiphenylsilyl)oxy)hept-1-yn-4-ol in a Continuous Packed-Bed Reactor, a Key Intermediate for Eribulin Synthesis
Krishna AS, et al.
Organic Process Research & Development, 24(11), 2657?2664-2657?2664 (2020)
An improved process for the preparation of ethyl-(R)-2-hydroxy-4-phenylbutyrate, (R)-HPB ester by lipase from Thermomyces lanuginosus
Basetty S, et al.
bioresource technology reports, 101163-101163 (2022)

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.