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T8656

Sigma-Aldrich

Thiourea

ACS reagent, ≥99.0%

Sinonimo/i:

Sulfourea, Thiocarbamide

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About This Item

Formula condensata:
NH2CSNH2
Numero CAS:
62-56-6
Peso molecolare:
76.12
Beilstein:
605327
Numero CE:
200-543-5
Numero MDL:
MFCD00008067
Codice UNSPSC:
12352100
ID PubChem:
24900549
NACRES:
NA.21

Grado

ACS reagent

Livello qualitativo

200

Saggio

≥99.0%

Residuo alla calcinazione

≤0.1% (as SO4)

Perdita

≤0.5% loss on drying, 105°C, 2h

Punto di fusione

170-176 °C (lit.)
174-177 °C

Solubilità

H2O: passes test

Stringa SMILE

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
UMGDCJDMYOKAJW-UHFFFAOYSA-N

Informazioni sul gene

mouse ... Ephx2(13850)

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Categorie correlate

Descrizione generale

Thiourea is an analogue of urea containing sulphur.

Applicazioni

Thiourea has been used:
  • as a component of lysis buffer for liver tissue homogenization
  • in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay
  • in rehydration buffer for protein extraction

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Azioni biochim/fisiol

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

Avvertenze

Warning

Indicazioni di pericolo

H302,H351,H361fd,H411

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
0000362337
0000394688
0000394689
0000393764
0000393766

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Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches
Gupta YR, et al.
Aquaculture and Fisheries, 1(2), 15-23 (2016)
Investigation of protein-tyrosine phosphatases by in-gel assays.
Markova B, et al.
Methods, 35(1), 22-27 (2005)
Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium
Osunlaja AA
International Journal of ChemTech Research, 4(2), 609-617 (2012)
Mireille Vonlanthen et al.
The Journal of organic chemistry, 78(8), 3980-3988 (2013-03-09)
Proof that sulfur is a viable reporting element for the development of fluorescent chemosensors for metal ions is presented. To date, the majority of metal-responsive fluorescent chemosensors have relied on metal-nitrogen coordination to provide a fluorescence response, most commonly by
Shrinivas Venkataraman et al.
Macromolecular rapid communications, 34(8), 652-658 (2013-03-14)
Readily water-soluble PEGylated amphiphiles containing bis-thiourea-based molecular recognition units at the interface of hydrophobic and hydrophilic blocks are developed. Self-assembly of these amphiphiles is found to be dependent on the exact chemical composition of the hydrophobic component. Elongated, spherical, and
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