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Q0132

Quinine sulfate

meets USP testing specifications, monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)

Sinonimo/i:

Quinine hemisulfate salt monohydrate, Quinine sulfate (2:1) (salt) dihydrate

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About This Item

Formula empirica (notazione di Hill):
C20H24N2O2 · 0.5H2O4S · H2O
Numero CAS:
Peso molecolare:
391.47
Beilstein:
6113937
Numero MDL:
Codice UNSPSC:
12352210
ID PubChem:
NACRES:
NA.21

agenzia

USP/NF
meets USP testing specifications

PM

monograph mol wt. 782.94

Punto di fusione

~225 °C (dec.) (lit.)

Spettro attività antibiotica

parasites

Modalità d’azione

enzyme | inhibits

Stringa SMILE

O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5

InChI

1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
ZHNFLHYOFXQIOW-LPYZJUEESA-N

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Applicazioni

Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.

Azioni biochim/fisiol

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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