77253

Heptafluorobutyric anhydride

for GC derivatization, LiChropur^™, ≥99.0%

• Sinonimo/i: HFAA, HFBA, Perfluorobutyric anhydride
• Formula condensata: (CF₃CF₂CF₂CO)₂O
• Numero CAS: 336-59-4
• Peso molecolare: 410.06
• Beilstein: 856036
• Numero CE: 206-410-8
• Numero MDL: MFCD00000432
• Codice UNSPSC: 12000000
• ID PubChem: 329767572
• NACRES: NA.22

Proprietà

• Grado: derivatization grade ((GC derivatization)); for GC derivatization
• Livello qualitativo: 100
• Saggio: ≥99.0% (GC); ≥99.0%
• Stato: liquid
• Qualità: LiChropur^™
• Impiego in reazioni chimiche: reagent type: derivatization reagent; reaction type: Acylations
• tecniche: gas chromatography (GC): suitable
• Indice di rifrazione: n20/D 1.287 (lit.)
• P. ebollizione: 108-110 °C (lit.)
• Punto di fusione: −43 °C (lit.)
• Densità: 1.674 g/mL at 20 °C (lit.); 1.674 g/mL at 20 °C
• Stringa SMILE: FC(F)(F)C(F)(F)C(F)(F)C(=O)OC(=O)C(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C8F14O3/c9-3(10,5(13,14)7(17,18)19)1(23)25-2(24)4(11,12)6(15,16)8(20,21)22; UFFSXJKVKBQEHC-UHFFFAOYSA-N

Descrizione

Descrizione generale

Heptafluorobutyric anhydride is a perfluoroacylated acylation reagent, that forms stable, volatile derivatives with alcohols, amines, and phenols. It is majorly used to prepare electron-capturing derivatives for GC/electron capture detection. It is generally used with an acid scavenger, to help drive the reaction to completion and to prevent column damage from acidic by-products of the derivatization reaction. It is also used for the frequent testing of drugs of abuse such as, amphetamines and phencyclidine by GC-MS technique.

Applicazioni

Learn more in the Product Information

Confezionamento

Clear borosilicate glass, high hydrolytic resistance (Type I)

Risultati analitici

Suitable for derivatization of aldosterone, digoxin, digitoxin and metabolites, estradiol, postaglandins F_1α and F_2α, 3-oxo-Δ⁴-steroids, steroids and testosterone.

Altre note

HFAA acylates amines, amino acids and other compounds. HFBA derivatives are highly volatile: used in GC separation

Reagent for 3-enol heptafluorobutyrate, heptafluorobutyrate, heptafluorobutyryl, 17-heptafluorobutyryl and 17-heptafluorobutyrate.

Note legali

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H314
• Consigli di prudenza: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Classi di pericolo: Skin Corr. 1B
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter