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43073

Supelco

Paracetamol β-D-glucuronide

analytical standard

Sinonimo/i:

p-Acetamidophenyl β-D-glucuronide, Acetaminophen glucuronide

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About This Item

Formula empirica (notazione di Hill):
C14H17NO8
Numero CAS:
16110-10-4
Peso molecolare:
327.29
Beilstein:
46644
Numero MDL:
MFCD03094680
Codice UNSPSC:
41116107
ID PubChem:
329756303
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.5% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤12.0% water

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O[C@@H]1[C@@H](O)[C@H](OC2=CC=C(NC(C)=O)C=C2)O[C@H](C(O)=O)[C@H]1O

InChI

1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1
IPROLSVTVHAQLE-BYNIDDHOSA-N

Categorie correlate

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Choose from one of the most recent versions:

Certificati d'analisi (COA)

Lot/Batch Number
BCCM2421
BCCH6221
BCCG3564
BCCF0007
BCCC7383

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Sigma-Aldrich

N1627

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Sigma-Aldrich

A3035

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Cristina Barosa et al.
Magnetic resonance in medicine, 70(2), 315-319 (2012-10-02)
Plasma glucose (2) H-enrichment in positions 5 ((2) H5) and 2 ((2) H2) from deuterated water ((2) H2 O) provides a measure of the gluconeogenic contribution to endogenous glucose production. Urinary glucuronide analysis can circumvent blood sampling but it is
Marie Lecoeur et al.
Talanta, 205, 120108-120108 (2019-08-28)
In this study, a capillary electrophoresis-tandem mass spectrometry method combining efficient separation and sensitive detection has been developed and validated, for the first time, to quantify acetaminophen and five of its metabolites in urine samples. Optimization of the method has
Michael Ganetsky et al.
Journal of clinical pharmacology, 53(4), 413-420 (2013-02-26)
Acetaminophen poisoning is the most frequent cause of acute hepatic failure in the US. Toxicity requires reductive metabolism of acetaminophen, primarily via CYP2E1. Liquid acetaminophen preparations contain propylene glycol, a common excipient that has been shown to reduce hepatocellular injury
Jialin Xu et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(2), 259-266 (2011-10-28)
UDP-glucuronosyltransferases (Ugt) catalyze phase II conjugation reactions with glucuronic acid, which enhances chemical polarity and the elimination from the body. Few studies have addressed whether Ugt expression and activity are affected by liver disease, such as steatosis. The purpose of
María L Ruiz et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(11), 2060-2066 (2007-08-10)
The effect of spironolactone (SL) administration on 17alpha-ethynylestradiol (EE)-induced cholestasis was studied, with emphasis on expression and activity of Mrps. Adult male Wistar rats were divided into the following groups: EE (5 mg/kg daily for 5 days, s.c.), SL (200
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