34002

(S)-(−)-Sulpiride

VETRANAL^®, analytical standard

• Sinonimo/i: (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, Levosulpiride
• Formula empirica (notazione di Hill): C₁₅H₂₃N₃O₄S
• Numero CAS: 23672-07-3
• Peso molecolare: 341.43
• Numero MDL: MFCD00055220
• Codice UNSPSC: 41116107
• ID PubChem: 329754747
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Nome Commerciale: VETRANAL^®
• Durata: limited shelf life, expiry date on the label
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Punto di fusione: 183-186 °C (lit.)
• applicazioni: forensics and toxicology; pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
• InChI: 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1; BGRJTUBHPOOWDU-NSHDSACASA-N

Descrizione

Descrizione generale

(S)-(−)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects.[1][2] It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.[2]

Applicazioni

(S)-(−)-Sulpiride may be used as an analytical reference standard for the determination of the drug, in biological samples[3][4] using hydrophilic interaction liquid chromatography−tandem mass spectrometry (HILIC−MS/MS)[3] and reversed-phase high-performance liquid chromatography with fluorescence detection (HPLC-FD).[4]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

D₂ dopamine receptor antagonist; antipsychotic.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)