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01542

Supelco

Chrysophanol

analytical standard

Sinonimo/i:

1,8-Dihydroxy-3-methylanthraquinone, 3-Methylchrysazin, Chrysophanic acid

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About This Item

Formula empirica (notazione di Hill):
C15H10O4
Numero CAS:
481-74-3
Peso molecolare:
254.24
Beilstein:
1252300
Numero CE:
207-572-2
Numero MDL:
MFCD00001208
Codice UNSPSC:
85151701
ID PubChem:
329747324
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

192-196 °C

Compatibilità

conforms to structure for Proton NMR spectrum

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1

InChI

1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
LQGUBLBATBMXHT-UHFFFAOYSA-N

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Descrizione generale

Chrysophanol is an anthraquinone compound and occurs naturally in Chinese herb Rheum officinale. It shows antimicrobial activity, and is an active component in many crude drugs having purgative properties.

Applicazioni

It may be used as reference standard in analyzing bioactive components (hyperin, nobiletin, hesperidin, emodin, chrysophanol, resveratrol, curcumine, and physcion) in Danning tablets using HPLC-UV and HPLC-ESI-MS.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

This compound is commonly found in plants of the genus: aloe

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Choose from one of the most recent versions:

Certificati d'analisi (COA)

Lot/Batch Number
BCCL5539
BCCK3465
BCCJ5750
BCCG0998
BCCF5803

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Slide 1 of 6

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Physcion phyproof® Reference Substance

PHL89757

Physcion

Emodin United States Pharmacopeia (USP) Reference Standard

USP

1235059

Emodin

Rhein

Sigma-Aldrich

R7269

Rhein

Aloe-emodin phyproof® Reference Substance

PHL89157

Aloe-emodin

Diacerein impurity B European Pharmacopoeia (EP) Reference Standard

Y0001596

Diacerein impurity B

Emodin 8-glucoside ≥95% (LC/MS-UV)

Sigma-Aldrich

SMB00546

Emodin 8-glucoside

Chrysophanol, an antimicrobial anthraquinone from the root extract of Colubrina greggii.
Garcia-Sosa, Karlina, et al.
Journal of the Mexican Chemical Society, 50.2, 76-78 (2006)
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells.
Lu CC
Molecular Nutrition And Food Research, 54(7), 967-976 (2010)
Myung Sun Lee et al.
Phytotherapy research : PTR, 25(6), 833-837 (2010-11-23)
Inactivation of epidermal growth factor receptor (EGFR) is a prime method used in colon cancer therapy. Here it is shown that chrysophanic acid, a natural anthraquinone, has anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked
Simultaneous analysis of eight bioactive compounds in Danning tablet by HPLC-ESI-MS and HPLC-UV.
Liu R
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1007-1012 (2007)
Su-Jin Kim et al.
Molecules (Basel, Switzerland), 15(9), 6436-6451 (2010-09-30)
Chrysophanol is a member of the anthraquinone family and has multiple pharmacological effects, but the exact mechanism of the anti-inflammatory effects of chrysophanol has yet to be thoroughly elucidated. In this study, we attempted to determine the effects of chrysophanol
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