Product HX0514 is from bovine testes.
HX0514
Hyaluronidase
Sinonimo/i:
Hyaluronidase
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1 PKG
232,00 €
232,00 €
Spedizione prevista il09 maggio 2025Dettagli
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Cambia visualizzazione
1 PKG
232,00 €
About This Item
232,00 €
Spedizione prevista il09 maggio 2025Dettagli
Prodotti consigliati
Coniugato
conjugate (Glucosaminoglycan)
Livello qualitativo
Stato
powder
Attività specifica
≥300 units/mg dry wt.
Produttore/marchio commerciale
Calbiochem®
Condizioni di stoccaggio
OK to freeze
Colore
white
Condizioni di spedizione
ambient
Temperatura di conservazione
−20°C
Descrizione generale
300 units/mg minimum, 50,000 units/vial. Suitable for biochemistry grade.
Specifications:Activity: 300NF U/mg min
Intended for laboratory and manufacturing use only. Not for drug, food, or household use.
Specifications:Activity: 300NF U/mg min
Intended for laboratory and manufacturing use only. Not for drug, food, or household use.
Applicazioni
Hyaluronidase has been used:
- to enzymatically remove extra-cellular matrix (ECM) to assess the lateral diffusion of the synaptic a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR)[1]
- to study the effects of 4-methylumbelliferone (4MU)/ hyaluronidase (HLX)-mediated depletion of the CD44/hyaluronan complex on trastuzumab binding in JIMT1 breast cancer xenografts[2]
- as a component of Hank′s balanced salt solution (HBSS) medium to digest fetal intestine tissue[3]
Azioni biochim/fisiol
Hyaluronidase is an endoglycosidase that degrades hyaluronic acid (HA), a component of the extracellular matrix. It is used to enhance drug diffusion and reverse the effects of HA filler injections. Hyaluronidases dissolve the subcutaneous nodules and can correct excessive quantities of injected filler. It eliminates the cumulus-corona-oocyte complex formed during intracytoplasmic sperm injection. Hyaluronidase inhibits tissue damage after the extravasation of several substances. It is used for reducing edema treating vitreous hemorrhage.[4]
Definizione di unità
One unit is based on the change in absorbency (turbidity) at 540 nm of an internal standard assayed concurrently with each lot. Internal standard replaces USP/NF reference no longer available.
Stato fisico
Dialyzed, lyophilized powder, not less than300 units per mg (dry weight).
Note legali
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Resp. Sens. 1
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I clienti hanno visto anche
Maurizio Cavallini et al.
Aesthetic surgery journal, 33(8), 1167-1174 (2013-11-08)
Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive
Alexander D B Ross et al.
STAR protocols, 2(2), 100597-100597 (2021-06-26)
Here, we describe protocols for the preparation and dissociation of human fetal and pediatric intestinal tissue to a high-viability epithelial single-cell suspension. This epithelium-enriched single-cell suspension can then be used to generate single-cell RNA sequencing data as well as to
Sang Hak Lee et al.
eLife, 6 (2017-07-28)
Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a large mobile extrasynaptic AMPAR pool. Using super-resolution microscopy, we examined how fluorophore size and photostability affected AMPAR trafficking outside of, and within, post-synaptic densities (PSDs) from rats. Organic fluorescent
Patricia M R Pereira et al.
Molecular pharmaceutics, 17(1), 327-337 (2019-12-06)
Human epidermal growth factor receptor 2 (HER2) is a biomarker in breast cancer, and its overexpression is required to initiate therapies using HER2-targeted antibodies. Although trastuzumab is one of the most effective therapeutic antibodies in HER2-overexpressing breast cancer, a significant
Articoli
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
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what is its source?
1 risposta-
Utile?
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What is the appropriate way to reconstitute this? In what medium and at what concentration? Is there an information sheet that provides this information?
1 risposta-
The enzyme can be reconstituted at 1mg/ml in 0.1M Sodium phosphate buffer, pH 5.3 with 0.15M sodium chloride. Stock solutions can be aliquoted and frozen for several months at -20C.
Stock solutions prepared in water (30units/ml) are stable for up to 2 weeks at 4°C and stock solutions prepared in 500 mM acetate buffer, pH 6.0, are stable for up to 1 month at 4°C.
It is recommended to make hyaluronidase solutions fresh. The lyophilized powder is very stable, at least 2 years when stored frozen -20C. This product does not contain a product information sheet.
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