Our R&D team conducted spike recovery and dilution linearity tests in rat serum samples. The sequence for both rat and mouse is identical. Although we attempted to develop this kit for both rat and mouse, the recovery in rats was considerably lower compared to mice. As a result, we do not recommend this kit for use with rats. Verification tests were not carried out in cerebrospinal fluid (CSF) or rat brain samples to assess potential improvement in recovery for other sample types.
HNDG4MAG-36K
MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 4 - Neuroscience Multiplex Assay
The analytes available for this multiplex kit are: Amyloid β40, Amyloid β42, GDNF, sRAGE, S100B.
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About This Item
Codice UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Prodotti consigliati
Livello qualitativo
Reattività contro le specie
human
Produttore/marchio commerciale
Milliplex®
assay range
accuracy: 84-108%
standard curve range: 14-10,000 pg/mL
(S100B)
standard curve range: 21-15,000 pg/mL
(sRAGE)
standard curve range: 27-20,000 pg/mL
(Amyloid β42)
standard curve range: 3-2,500 pg/mL
(Amyloid β40)
standard curve range: 7-5,000 pg/mL
(GDNF)
tecniche
multiplexing: suitable
Metodo di rivelazione
fluorometric (Luminex xMAP)
Condizioni di spedizione
wet ice
Descrizione generale
The MILLIPLEX® Human Neurodegenerative Bead Panel 4 is to be used for the simultaneous quantification of the following 5 analytes in any combination in human cerebrospinal fluid (CSF): S100B, Amyloid β40 (Aβ1-40), Amyloid β42 (Aβ1-42), sRAGE, and GDNF. This kit is not validated for testing serum or cell culture supernatants.
Panel Type: Neuroscience
Panel Type: Neuroscience
Specificità
Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Applicazioni
- Analytes: Amyloid β40, Amyloid β42, GDNF, sRAGE, S100B
- Recommended Sample type: CSF
- Recommended Sample dilution: 1:3
- Assay Run Time: Overnight
- Research Category: Neuroscience
Caratteristiche e vantaggi
Design your multiplex kit by choosing available analytes within this panel.
Confezionamento
Everything you need in a single kit.
Stoccaggio e stabilità
Recommended storage for kit components is 2 - 8°C.
Altre note
Sensitivity: Refer to kit protocol for sensitivities of individual analytes.
Note legali
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
Codice della classe di stoccaggio
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Nicholas J Justice et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(6), 2612-2623 (2015-02-13)
Recent studies have found that those who suffer from posttraumatic stress disorder (PTSD) are more likely to experience dementia as they age, most often Alzheimer's disease (AD). These findings suggest that the symptoms of PTSD might have an exacerbating effect
Contenuto correlato
Learn how multiplex detection of Alzheimer’s disease biomarkers, using the MILLIPLEX® Human Amyloid Beta and Tau Magnetic Bead Panel, allows for a different perspective on neurodegenerative disease research.
Neuroscience multiplex assays, such as MILLIPLEX® multiplex assays, enable simultaneous measurement of neuroscience-related biomarkers to gain a better picture of neurodegenerative diseases, neurological disorders, and neuropeptide/neurohormone signaling.
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Is the Milliplex Mouse Amyloid Beta Panel (MABMAG-83K) suitable for testing rat samples?
1 risposta-
Utile?
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What is the reason that GLP-1 total and active cannot be run together in HMHEMAG-34K?
1 risposta-
The same capture is used for both total and active GLP-1; however, the detection is specific to either total or active GLP-1.
Utile?
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