8.55065
NovaSyn® TG carboxy resin
Novabiochem®
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About This Item
Codice UNSPSC:
13111023
Prodotti consigliati
Nome Commerciale
NovaSyn® TG
Novabiochem®
Stato
beads
Impiego in reazioni chimiche
reaction type: Fmoc solid-phase peptide synthesis
Produttore/marchio commerciale
Novabiochem®
applicazioni
peptide synthesis
Temperatura di conservazione
2-30°C
Descrizione generale
NovaSynTG carboxy resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol, in which the ends of the PEG chains have been functionalized with carboxyl groups. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water [1-3], making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis.
This support can be used to immobilize alcohols through formation of an ester with the resin-bound carboxy group. Cleavage can be effected either by saponification, hydrazinolysis or reduction with LiBH4 .
In studies on the synthesis of furans via intramolecular radical cyclization, NovaSynTG carboxy resin was found to give superior results to carboxy polystyrene [4]. This observation was attributed to the notion that, in the PEG-based support, the radical intermediates would be prevented, by virtue of being tethered to the ends of PEG chains, from approaching and thus being quenched by the benzylic protons of the polystyrene backbone.
The product number for this product was previously 01-64-0097.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
This support can be used to immobilize alcohols through formation of an ester with the resin-bound carboxy group. Cleavage can be effected either by saponification, hydrazinolysis or reduction with LiBH4 .
In studies on the synthesis of furans via intramolecular radical cyclization, NovaSynTG carboxy resin was found to give superior results to carboxy polystyrene [4]. This observation was attributed to the notion that, in the PEG-based support, the radical intermediates would be prevented, by virtue of being tethered to the ends of PEG chains, from approaching and thus being quenched by the benzylic protons of the polystyrene backbone.
The product number for this product was previously 01-64-0097.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Linkage
Replaces: 01-64-0097
Risultati analitici
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of nitrogen after derivatization with methylamine): 0.30 - 0.60 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
130 µm beads
Appearance of substance (visual): beads
Loading (determined by elemental analysis of nitrogen after derivatization with methylamine): 0.30 - 0.60 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
130 µm beads
Note legali
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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