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204903

Sigma-Aldrich

Anti-Complement 5b-9 Rabbit pAb

Anti-Complement 5b-9 Rabbit pAb

liquid, Calbiochem®

Sinonimo/i:

Anti-Terminal Complement Complex, Anti-Membrane Attack Complex, Anti-MAC

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1 MG
460,00 €

460,00 €


Spedizione prevista il18 aprile 2025Dettagli


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Cambia visualizzazione
1 MG
460,00 €

About This Item

Codice UNSPSC:
12352203
NACRES:
NA.43

460,00 €


Spedizione prevista il18 aprile 2025Dettagli


Richiedi un ordine bulk

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

liquid

contiene

≤0.1% sodium azide as preservative

Reattività contro le specie

human, mouse

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

OK to freeze
avoid repeated freeze/thaw cycles

Isotipo

IgG

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Descrizione generale

Protein A purified rabbit polyclonal antibody. Recognizes the C5b-C9 complement component complex.
Recognizes complement component complex Cb5-C9.
This Anti-Complement 5b-9 Rabbit pAb is validated for use in Frozen Sections, Immunofluorescence, Paraffin Sections, Radial Immunodiffusion for the detection of Complement 5b-9.

Immunogeno

Human
purified human SC5b-9 complex

Applicazioni

Frozen Sections (see application references)

Immunofluorescence (see comments)

Paraffin Sections (see comments, heat pre-treatment required)

Radial Immunodiffusion (use undiluted)

Confezionamento

Please refer to vial label for lot-specific concentration.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In PBS, pH 7.2.

Ricostituzione

Following intial thaw, aliquot and freeze (-20°C).

Altre note

By immunodiffusion the antibody is monospecific for C5b-9 complex in purified form or present in cobra venom factor activated human serum. There is no reactivity vs. non-activated normal human serum or plasma. Also reported to work for immunofluorescence. This antibody has been shown to work for formalin-fixed paraffin sections; use of citrate buffer and a pressure cooker for 1 min is required for antigen retrieval. Antibody should be titrated for optimal results in individual systems.
Schafer, H., et al. 1986. J. Immunol.137, 1945.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Xiao Han et al.
International journal of molecular sciences, 18(1) (2017-01-21)
The initiator of extrinsic coagulation, tissue factor (TF), and its non-coagulant isoform alternatively spliced TF (asTF) are closely associated with tumor development. In the tumor microenvironment, the role of TF-induced coagulation in tumor progression remains to be fully elucidated. Using
E Panayiotou et al.
Biochemistry and biophysics reports, 8, 48-54 (2017-09-29)
Penetrance and age of onset of ATTRV30M amyloidotic neuropathy varies significantly among different populations. This variability has been attributed to both genetic and environmental modifiers. We studied the effect of genetic background on phenotype in two lines of transgenic mice
Ting-Ting Gao et al.
International journal of ophthalmology, 8(4), 675-680 (2015-08-27)
To investigate the expression of complement factors in the posterior scleral fibroblasts of guinea pigs with negative lens-defocused myopia. Eighteen guinea pigs were assigned randomly to two groups: the negative lens-defocused group (NLD group, n=9) and the normal control without
Todor Tschongov et al.
Frontiers in immunology, 15, 1383123-1383123 (2024-05-27)
Most drugs that target the complement system are designed to inhibit the complement pathway at either the proximal or terminal levels. The use of a natural complement regulator such as factor H (FH) could provide a superior treatment option by
Maria Martin et al.
Kidney international reports, 9(7), 2227-2239 (2024-07-31)
Atypical hemolytic uremic syndrome (aHUS) is a complement system (CS)-mediated ultrarare disease that manifests as thrombotic microangiopathy (TMA) with preferential small kidney vessels involvement. Transient CS activation is also observed in secondary TMA or in patients at risk of developing

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  1. New York, NY
    • Recensione 1
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    5 su 5 stelle.

    Works well

    -IHC (1:100) for 16 Hours @ 4C
    -Secondary (1:400) for 1 Hours @ RT
    -Long wash times in PBST
    -positive control diseased kidney, 90% damaged glomeruli

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