808865
Gold nanoparticles
40 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O
Sinonimo/i:
Biotin Gold
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0.5 ML
319,00 €
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Cambia visualizzazione
0.5 ML
319,00 €
About This Item
Codice UNSPSC:
12141717
NACRES:
NA.23
Prodotti consigliati
Materiali
PEG 5000
Livello qualitativo
Stato
dispersion in H2O
nanoparticles
Composizione
, 3.58E12 particles/mL
Confezionamento
pkg of 0.5 mL
Condizioni di stoccaggio
do not freeze
Concentrazione
2.33 mg/mL in H2O
OD
50
Area superficiale
7.74 m2/g
Diametro
40 nm
pH
5-7
Densità
1.00 g/cm3
peak SPR wavelength
530 nm
Gruppo funzionale
biotin
Temperatura di conservazione
2-8°C
InChI
1S/Au
PCHJSUWPFVWCPO-UHFFFAOYSA-N
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Categorie correlate
Descrizione generale
Gold nanoparticles PEG 5000 biotin terminated.The preparation of biotinylated gold nanoparticles involves two surface modification steps. First the carboxyl-terminated alkanethiol is attached to the surface of gold nanoparticles via chemisorption in the presence of a stabilizing agent. This step is followed by the reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecanediamine and 2-(2-aminoethoxy)ethanol.[1]
Applicazioni
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent and ranges from 515-520nm for a 5nm particle to 572nm for a 100nm particle.
Gold nanoparticles 40 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19.[2][3] It can also be used in the detection of pathogens for biosensing applications.[4][5] AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.[6][7]
Note legali
Product of CytoDiagnostics, Inc.
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Controlled and reversible aggregation of biotinylated gold nanoparticles with streptavidin.
Aslan K, et al.
The Journal of Physical Chemistry B, 108(40), 15631-15639 (2004)
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Heo DN, et al.
Biomaterials, 33(3), 856-866 (2012)
Colorimetric biosensing of pathogenss using gold nanoparticles
Verma MS, et al.
Biotechnology Advances, 33(6), 666-680 (2015)
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 33(6), 666-680 (2020)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Itani R, et al.
Theranostics, 10(13), 5932-5932 (2020)
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