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Sigma-Aldrich

Bromomethyl methyl ether

technical grade, 90%

Sinonimo/i:

1-Bromomethyl methyl ether, Bromomethoxymethane, Methoxymethyl bromide

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5 G
30,20 €
25 G
86,10 €

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5 G
30,20 €
25 G
86,10 €

About This Item

Formula condensata:
BrCH2OCH3
Numero CAS:
Peso molecolare:
124.96
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

30,20 €


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Grado

technical grade

Livello qualitativo

Saggio

90%

Stato

liquid

Indice di rifrazione

n20/D 1.456 (lit.)

P. ebollizione

87 °C (lit.)

Densità

1.531 g/mL at 25 °C (lit.)

Gruppo funzionale

bromo
ether

Temperatura di conservazione

2-8°C

Stringa SMILE

COCBr

InChI

1S/C2H5BrO/c1-4-2-3/h2H2,1H3
JAMFGQBENKSWOF-UHFFFAOYSA-N

Categorie correlate

Applicazioni

Bromomethyl methyl ether was used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506[1]. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone[2].

Avvertenze

Warning

Classi di pericolo

Acute Tox. 4 Dermal - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

80.6 °F - closed cup

Punto d’infiammabilità (°C)

27 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

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Nuclear analogs of β-lactam antibiotics. XVI. Aldol condensations of N-protected 4-tritylthio-2-azetidinones.
Martel A, et al.
Canadian Journal of Chemistry, 61(3), 613-618 (1983)
Enantioselective synthesis of the C (18)-C (35) segment of immunosuppressant FK-506 using efficient new methodology.
Corey EJ and Huang H-C.
Tetrahedron Letters, 30(39), 5235-5238 (1989)
Archana Prasad et al.
Scientific reports, 6, 39490-39490 (2016-12-22)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with aggregation of TAR DNA-binding protein-43 (TDP-43) in neuronal cells and manifests as motor neuron dysfunction &muscle atrophy. The carboxyl-terminal prion-like domain of TDP-43 can aggregate in vitro into toxic

Domande

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

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