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Merck

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Sinonimi:
EAAT2, GLT-1
Specie:
ID UniProtKB:
ID gene:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

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Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Specie
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Specie
rat, human
(±)-AMPA, solid,
Specie
rat
Kainic acid monohydrate, ≥99% (TLC),
Specie
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Specie
rat, human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-trasportatore del glutammato, gliale, serum, Chemicon®,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anticorpo anti-trasportatore degli amminoacidi eccitatori 2, clone G6, clone G6, from mouse,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Dihydrokainic acid, ≥98% (HPLC), powder,
Specie
rat, human
(Aminomethyl)phosphonic acid, 99%,
Specie
rat, human
Acido L-glutammico, ReagentPlus®, ≥99% (HPLC),
Specie
rat, human
Acido L-glutammico, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Specie
rat, human
Acido L-glutammico, BioUltra, ≥99.5% (NT),
Specie
rat, human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human SLC1A2,
Specie
human