Passa al contenuto
Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Sinonimi:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Specie:
ID UniProtKB:
ID gene:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
Buspirone hydrochloride, ,
Specie
human
Buspirone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Buspirone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Buspirone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Small Molecule - Allosteric Modulator

Numero di prodotto
Descrizione
Specie
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
1-(3-Chlorophenyl)piperazine hydrochloride, 99%,
Specie
rat
1-(3-Methoxyphenyl)piperazine, 95%,
Specie
rat
WAY-100635 maleate salt, powder,
Specie
human
GR 103691, ≥98% (HPLC), solid,
Specie
rat
1-(4-Methoxyphenyl)piperazine, 97%,
Specie
mouse, rat

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Serotonin antibody produced in rabbit, whole antiserum,
Reattività con
human, rat
Applicazione
immunohistochemistry
Anti-Serotonin Antibody, clone YC5/45, culture supernatant, clone YC5/45, Chemicon®,
Reattività con
human, lizard, mouse, pig, rabbit, rat
Applicazione
immunohistochemistry
Anti-HTR1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Serotonin Receptor 1A Antibody, serum, Chemicon®,
Reattività con
rat
Applicazione
immunohistochemistry
Anti-5HT1A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
Trazodone hydrochloride, ≥99% (HPLC), powder,
Specie
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Specie
human
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Vilazodone hydrochloride, ≥98% (HPLC),
Specie
human
Vilazodone hydrochloride solution, 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®,
Specie
human
1,2,3,4-Tetrahydroisoquinoline, 95%,
Specie
rat, human
Trazodone hydrochloride, ≥99% (HPLC), powder,
Specie
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

Numero di prodotto
Descrizione
Specie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

Numero di prodotto
Descrizione
Specie
Mifepristone, ≥98%,
Specie
human, mouse, rat
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

Small Molecule - Precursor

Numero di prodotto
Descrizione
Specie
5-Hydroxy-L-tryptophan, powder,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
Serotonin Receptor 1A, Control Peptide for AB5406, ,
Specie
rat