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Merck

CHRNB2

cholinergic receptor, nicotinic, beta 2 (neuronal)

Sinonimi:
EFNL3, nAChRB2
Specie:
ID UniProtKB:
ID gene:
  • Human(1141) Summary: Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]
  • Mouse(11444) cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
  • Rat(54239) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • dog(490443) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • naked mole-rat(101704220) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • chicken(395605) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • cow(517519) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • sheep(101104117) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • domestic guinea pig(100730761) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • domestic cat(101084932) cholinergic receptor, nicotinic, beta 2 (neuronal)

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
S(−)-Nicotine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
(−)-Nicotine hemisulfate salt, ≥95% (TLC), ~35 % (w/v) in H2O (based on free base),
Specie
human
(−)-Nicotine, PESTANAL®, analytical standard,
Specie
human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Specie
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Specie
human, mouse, rat

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
1-(4-Pyridyl)piperazine, ≥97.0% (GC),
Specie
rat
Acido nicotinico, ≥99.5% (HPLC),
Specie
rat, human
Acido nicotinico, ≥98%,
Specie
rat, human
Acido nicotinico, analytical standard,
Specie
rat, human
Acido nicotinico, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%,
Specie
rat, human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CHRNB2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, human, mouse, pig
Applicazione
western blot
Anti-CHRNB2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
human, pig
Applicazione
western blot

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
Tetraethylammonium chloride, ≥98% (titration),
Specie
human
Hexamethonium bromide, ,
Specie
human
Hexamethonium chloride, solid (hygroscopic),
Specie
human
Kynurenic acid, ≥98%,
Specie
rat, human

Small Molecule - Mixed Agonist/Antagonist

Numero di prodotto
Descrizione
Specie
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Specie
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Specie
human, mouse, rat

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Chrnb2,
Specie
mouse
MISSION® esiRNA, targeting human CHRNB2,
Specie
human