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Merck

CHRM5

cholinergic receptor, muscarinic 5

Sinonimi:
HM5
Specie:
Human CHRM5 (1133), Mouse Chrm5 (213788), Rat Chrm5 (53949), naked mole-rat Chrm5 (101719201), Domestic Rabbit CHRM5 (100342984), dog CHRM5 (487472), Horse CHRM5 (100057856), cow CHRM5 (281686), sheep CHRM5 (101110766), domestic cat CHRM5 (101097246) ...Più
ID UniProtKB:
P08912, Q96RG7
ID gene:
  • Human(1133) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
  • Mouse(213788) cholinergic receptor, muscarinic 5
  • Rat(53949) cholinergic receptor, muscarinic 5
  • naked mole-rat(101719201) cholinergic receptor, muscarinic 5
  • Domestic Rabbit(100342984) cholinergic receptor, muscarinic 5
  • dog(487472) cholinergic receptor, muscarinic 5
  • Horse(100057856) cholinergic receptor, muscarinic 5
  • cow(281686) cholinergic receptor, muscarinic 5
  • sheep(101110766) cholinergic receptor, muscarinic 5
  • domestic cat(101097246) cholinergic receptor, muscarinic 5
  • chicken(428881) cholinergic receptor, muscarinic 5
  • domestic guinea pig(100379240) cholinergic receptor, muscarinic 5

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Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
P6503
Pilocarpine hydrochloride, ≥99% (titration), powder,
Specie
human
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Specie
human
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
Specie
human
O100
Oxotremorine M, solid,
Specie
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
S1875
(−)-Scopolamine hydrobromide trihydrate, ≥98% (HPLC), powder,
Specie
human
A0257
Atropine sulfate salt monohydrate, ≥97% (TLC), crystalline,
Specie
human
S8502
(−)-Scopolamine methyl bromide, ≥98% (HPLC), powder,
Specie
human
P8891
Propantheline bromide, ≥97% (TLC), powder,
Specie
human
S7882
(−)-scopolamina N-butilbromuro, ≥98% (TLC), powder,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
HPA013172
Anti-CHRM5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Specie
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Specie
human
51330
Harmaline, ≥95%,
Specie
human, rat

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
A138
Aminobenztropine, solid,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
HTS075M
ChemiScreen Membrane Preparation
Recombinant Human M5 Muscarinic Acetylcholine Receptor, Human M5 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU130281
MISSION® esiRNA, targeting human CHRM5,
Specie
human