11023AST
Astec® CHIROBIOTIC® V Chiral (5 μm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Szinonimák:
Vancomycin Chiral Column
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
41115700
eCl@ss:
32110501
NACRES:
SB.52
H × belső átmérő:
15 cm × 4.6 mm
részecskeméret:
5 μm
mátrix aktív csoport:
vancomycin phase
pórusméret:
100 Å
Mátrix:
High-purity silica gel particle platform
fully porous particle
fully porous particle
Javasolt termékek
Terméknév
Astec® CHIROBIOTIC® V Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
Minőségi szint
Ügynökség
suitable for USP L88
leírás
HPLC Column
termékcsalád
Astec®
kiszerelés
pkg of 1 ea
gyártó/kereskedő neve
Astec®
parameter
0-45 °C temperature
80-110 bar pressure (1200-1500 psi)
technika/technikák
HPLC: suitable
LC/MS: suitable
H × belső átmérő
15 cm × 4.6 mm
Mátrix
High-purity silica gel particle platform
fully porous particle
mátrix aktív csoport
vancomycin phase
részecskeméret
5 μm
pórusméret
100 Å
pH-tartomány
3.5-7.0
elválasztástechnika
chiral
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Általános leírás
Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC® V in the polar ionic mode. The CHIROBIOTIC® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.
- Bonded phase: Vancomycin
- Operating pH range: 3.5 - 7.0
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å (CHIROBIOTIC® V) or 200 Å (CHIROBIOTIC® V2)
Alkalmazás
- Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma and its application to pharmacokinetic study.: This study highlights the application of UFLC-MS/MS combined with Astec® CHIROBIOTIC® V Chiral HPLC Column for the enantioselective analysis of various therapeutic agents in rat plasma, providing a crucial methodological advancement for pharmacokinetic research ( Zhang et al., 2016).
Jogi információk
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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Chiral stability-indicating HPLC method for analysis of arotinolol in pharmaceutical formulation and human plasma
Sultan, Maha A., et al.
Arabian Journal of Chemistry, 3 (3), 147-153 (2010)
Hisham Hashem et al.
Journal of chromatography. A, 1218(38), 6727-6731 (2011-08-23)
In this study, a method for enantioseparation of terbutaline and salbutamol was established using Chirobiotic V column as a stationary phase. Polar ionic mode applying mobile phase containing ammonium nitrate in 100% ethanol, pH 5.1 was found to give the
Ana R Ribeiro et al.
Chemosphere, 95, 589-596 (2013-11-05)
Microbial degradation is the most important process to remove organic pollutants in Waste Water Treatment Plants. Regarding chiral compounds this process is normally enantioselective and needs the suitable analytical methodology to follow the removal of both enantiomers in an accurate
Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series
Rao, R. Nageswara, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879 (21), 1911-1916 (2011)
Victoria K H Barclay et al.
Journal of chromatography. A, 1269, 208-217 (2012-10-24)
A LC-MS/MS method for the chiral separation of metoprolol and two of its main metabolites, α-hydroxymetoprolol (α-OH-Met) and deaminated metoprolol (COOH-Met), in environmental water samples has been developed. The target bases, metoprolol and α-OH-Met, as well as the acidic metabolite
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