SAB5801005

Alpaca Anti-Mouse IgG(Fcγ) HRP single domain Antibody

recombinant Alpaca(VHH) Nano antibody

• Szinonimák: Recombinant Alpaca single variable domain secondary Nanobody
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: alpaca
• rekombináns: expressed in E. coli
• konjugátum: horse radish peroxidase (HRP)
• antitest forma: affinity purified immunoglobulin
• antitest terméktípus: secondary antibodies
• klón: polyclonal
• form: lyophilized solid
• molekulatömeg: 14 kDa
• faj reaktivitás: Alpaca, mouse
• technika/technikák: ELISA: 1:10000-1:50000; western blot: 1:10000-1:50000
• méret: 0.1 mL
• szín: colorless
• izotípus: VHH
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C

Leírás

Általános leírás

Alpaca Anti-Mouse IgG(Fcγ) HRP single domain Antibody is designed to specifically detect the Fc region of mouse IgG. It is a single domain recombinant antibody to mouse IgG(Fcγ fragment specific) coupled to HRP. Alpaca Anti-Mouse IgG(Fcγ) HRP single domain Antibody detects the Fc region of mouse IgG selectively but not with mouse IgM, or the Fab portion of mouse immunoglobulins.

Most monoclonal antibodies are generated in mouse. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mouse. Each isotype has a different heavy chain. Mouse IgG constitutes 75% of serum immunoglobulins, and IgG is the predominant form of first antibody produced from mouse. Mouse IgG consists of five subclasses-IgG1, IgG2a, IgG2b, IgG2c(inbred mouse strains with the Igh1-b allele have IgG2c isotype instead of IgG2a), IgG3. They are highly homologous and differ mainly in the hinge region. The whole IgG molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgG contains two heavy and light chains, and the heavy chain is about 50 KD and the light chain is about 25 KD. The common IgG is monomeric with a molecular weight of approximately 150 kD.

VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

Egyediség

Mouse IgG(Fcγ fragment specific)
Isotype: VHH domain of alpaca IgG2b/2c

Immunogen

Recombinant Alpaca single variable domain secondary nano antibody

Kiszerelés

100 μg in Glass bottle

Fizikai forma

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

Feloldás

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

Tárolás és stabilitás

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Protect from light. Stable for 12 months at -20°C

Egyéb megjegyzések

No cross-reactivity with mouse IgM, rabbit, human, cynomolgus, rat, goat IgG

Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H317,H412
• Óvintézkedésre vonatkozó mondatok: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Veszélyességi osztályok: Aquatic Chronic 3 - Skin Sens. 1
• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable