SAB5700980

Anti-MCM3 antibody produced in rabbit

• UNSPSC kód: 12352203
• NACRES: NA.43
• klón: monoclonal
• application: IHC; WB
• faj reaktivitás: mouse, rat, human
• technika/technikák: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest terméktípus: primary antibodies
• klón: monoclonal
• Forma: liquid
• faj reaktivitás: mouse, rat, human
• koncentráció: 0.4 mg/mL
• technika/technikák: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt elérési szám: P25205
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... MCM3(4172)

Leírás

Általános leírás

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

Immunogén

A synthesized peptide derived from human MCM3

Fizikai forma

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Biztonsági adatok

• Tárolási osztály kódja: 12 - Non Combustible Liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable