SAB4200370

Anti-PVRL4 antibody, Mouse monoclonal

clone N4.101.10, purified from hybridoma cell culture

• Szinonimák: Monoclonal Anti-Nectin-4/PVRL4 antibody produced in mouse, Monoclonal Anti-PVRL4 antibody produced in mouse, Anti-EDSS1, Anti-LNIR, Anti-Nectin-4, Anti-PRR4, Anti-PVRL4, Anti-Poliovirus receptor-related 4
• UNSPSC kód: 12352203
• NACRES: NA.41
• konjugátum: unconjugated
• application: FACS; ICC
• klón: N4.101.10, monoclonal
• faj reaktivitás: human
• citations: 3
• technika/technikák: flow cytometry: 5-10 μg/test using using 1x10⁶ MDA-MB-231 cells; immunocytochemistry: 2.5-5 μg/mL using using MDA-MB-231 cells

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 200
• konjugátum: unconjugated
• antitest forma: purified from hybridoma cell culture
• antitest terméktípus: primary antibodies
• klón: N4.101.10, monoclonal
• Forma: buffered aqueous solution
• faj reaktivitás: human
• koncentráció: ~1.0 mg/mL
• technika/technikák: flow cytometry: 5-10 μg/test using using 1x10⁶ MDA-MB-231 cells; immunocytochemistry: 2.5-5 μg/mL using using MDA-MB-231 cells
• izotípus: IgG1
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... PVRL4(81607)

Leírás

Általános leírás

Monoclonal Anti-Nectin-4/PVRL4 (mouse IgG1 isotype) is derived from the hybridoma R2.525.2 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human nectin4-Fc recombinant protein. Nectin-4 belongs to the family of Nectins. It forms homo-cis-dimers and then homo- or hetero-trans-dimers through the extracellular region in a Ca²⁺-independent manner. Nectin-4 is expressed in placenta, ductal breast carcinoma and lung adenocarcinomas. It is one of the plasma membrane components of adherens junctions.

Immunogén

human Nectin4/Fc recombinant protein

Alkalmazás

Monoclonal Anti-PVRL4 antibody produced in mouse has been used in immunocytochemistry and flow cytometry.

Biokémiai/fiziológiai hatások

Nectin-4 is involved in cell adhesion through trans homophilic and heterophilic interactions. Mutations in this gene are associated with ectodermal dysplasia-syndactyly syndrome type 1.

Fizikai forma

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable