SAB3701071

Anti-Mouse IgG (H+L), highly cross adsorbed antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• UNSPSC kód: 12352203
• NACRES: NA.46

Tulajdonságok

• biológiai forrás: goat
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: affinity isolated antibody
• antitest terméktípus: secondary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• faj reaktivitás: mouse
• koncentráció: 2.0 mg/mL
• technika/technikák: ELISA: suitable; immunohistochemistry: suitable; western blot: suitable
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C
• célzott transzláció utáni módosítás: unmodified

Leírás

Általános leírás

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a γ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical (called Fab fragments) and contain the antigen-binding activity. The third fragment (called Fc fragment) does not possess antigen-binding activity, but binds to cells and effector molecules. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.

Egyediség

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Goat Serum, Mouse IgG and Mouse Serum. No reaction was observed against Human Serum Proteins. Specificity was confirmed using ELISA at less than 0.3% cross reactivity against Human IgG.

Immunogen

Mouse IgG whole molecule

Fizikai tulajdonságok

Antibody format: IgG

Fizikai forma

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable