SAB1409054

Monoclonal Anti-FTL antibody produced in mouse

clone X1, purified immunoglobulin, buffered aqueous solution

• Szinonimák: MGC71996
• UNSPSC kód: 12352203
• NACRES: NA.41
• konjugátum: unconjugated
• application: ELISA (i); IF; IP; WB
• klón: X1, monoclonal
• faj reaktivitás: human
• citations: 2
• technika/technikák: immunoprecipitation (IP): suitable; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: X1, monoclonal
• Forma: buffered aqueous solution
• molekulatömeg: antigen 44.99 kDa
• faj reaktivitás: human
• technika/technikák: immunoprecipitation (IP): suitable; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL
• izotípus: IgG1κ
• NCBI elérési szám: BC004245
• UniProt elérési szám: P02792
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... FTL(2512)

Leírás

Általános leírás

Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. This gene encodes the light subunit of the ferritin protein. It is composed of 24 subunits of the heavy and light ferritin chains.(provided by RefSeq). In humans, the heavy H and the light L chains are made up of 183 and 175 amino acids, respectively. FTL (ferritin) is a heteropolymer, located on human chromosome 19q13. Ferritins centralize iron in their inner compartment as a bioavailable iron oxide biomineral.

Immunogén

FTL (AAH04245, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD

Biokémiai/fiziológiai hatások

Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
L-Ferritin subunits deliver the scaffold for a trinuclear peroxo-bridged cluster.

Fizikai forma

Solution in phosphate buffered saline, pH 7.4

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable