561300

E-Selectin, Human, Recombinant, CHO Cells

• Szinonimák: CD62E, ELAM-1
• UNSPSC kód: 12352202
• NACRES: NA.77
• gyártó/kereskedő neve: Calbiochem^®

Tulajdonságok

• Teszt: ≥95% (SDS-PAGE)
• Minőségi szint: 100
• Forma: lyophilized
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze
• szennyeződések: <1 EU/μg Endotoxin (EU/μg of E-Selectin)
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C

Leírás

Általános leírás

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLe^x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

Biokémiai/fiziológiai hatások

Shown to bind to E-selectin ligands on U937 cells.

Figyelmeztetés

Toxicity: Standard Handling (A)

Fizikai forma

Lyophilized from Dulbecco′s PBS with stabilizer.

Feloldás

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Reconstitute to 1 mg/ml with sterile H₂O.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2