233493

Coagulation Factor α-XIIa, Human Plasma

Coagulation Factor α-XIIa, Human Plasma, is a native coagulation factor α-XIIa prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation.

• Szinonimák: Coagulation factor
• UNSPSC kód: 12352202
• NACRES: NA.25

Tulajdonságok

• Minőségi szint: 100
• form: liquid
• specifikus aktivitás: 50 units/mg protein (clotting assay)
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze; avoid repeated freeze/thaw cycles
• kiszállítva: wet ice
• tárolási hőmérséklet: −70°C

Leírás

Általános leírás

Native coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.

Kiszerelés

Please refer to vial label for lot-specific concentration.

Figyelmeztetés

Toxicity: Standard Handling (A)

Fizikai forma

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Elkészítési megjegyzés

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Feloldás

Following initial thaw, aliquot and freeze (-70°C).

Analízis megjegyzés

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

homogeneous by SDS-PAGE

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable