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Merck

I5627

Sigma-Aldrich

异丙肾上腺素 盐酸盐

≥98.5% (TLC), powder, β-adrenoceptor agonist

别名:

(±)-异丙肾上腺素 盐酸盐, 1-(3′,4′-二羟基苯基)-2-异丙基氨基乙醇 盐酸盐, N-异丙基-DL-去甲肾上腺素 盐酸盐

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About This Item

经验公式(希尔记法):
C11H17NO3 · HCl
CAS号:
分子量:
247.72
Beilstein:
3917363
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

product name

异丙肾上腺素 盐酸盐,

mp

165-175 °C (dec.) (lit.)

起源

Sanofi Aventis

SMILES 字串

Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI 密鑰

IROWCYIEJAOFOW-UHFFFAOYSA-N

基因資訊

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相关类别

生化/生理作用

β-肾上腺素受体激活剂;增加胞质cAMP。

特點和優勢

该化合物在受体分类和信号转导手册中β-肾上腺素能受体页面中进行了详细介绍。想要浏览手册的其他页面, 请单击此处
该化合物是由Sanofi Aventis研发。想要浏览其他由制药公司开发的化合物以及已批准物/候选药物清单, 请单击此处

其他說明

仅供研究使用

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Na Tian et al.
Diabetes, 69(7), 1355-1367 (2020-04-17)
Obesity has recently become a prevalent health threat worldwide. Although emerging evidence has suggested a strong link between the pentose phosphate pathway (PPP) and obesity, the role of transketolase (TKT), an enzyme in the nonoxidative branch of the PPP that
Aaron M Ring et al.
Nature, 502(7472), 575-579 (2013-09-24)
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. So far, it has not been
Michael Schwarzl et al.
Critical care medicine, 41(12), e401-e410 (2013-08-22)
We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Randomized controlled prospective experimental study. Large animal facility, Medical University of Graz, Austria. Thirteen anesthetized and mechanically ventilated pigs. Lipopolysaccharide was administered for 4 hours. With
Eric M Jones et al.
eLife, 9 (2020-10-22)
The >800 human G protein-coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad structural conformations and various modes of signaling make it challenging to understand
Roshanak Irannejad et al.
Nature, 495(7442), 534-538 (2013-03-22)
A long-held tenet of molecular pharmacology is that canonical signal transduction mediated by G-protein-coupled receptor (GPCR) coupling to heterotrimeric G proteins is confined to the plasma membrane. Evidence supporting this traditional view is based on analytical methods that provide limited

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