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Merck

I0599990

异丙肾上腺素 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

异丙肾上腺素 盐酸盐, (±)-异丙肾上腺素 盐酸盐, 1-(3′,4′-二羟基苯基)-2-异丙基氨基乙醇 盐酸盐, N-异丙基-DL-去甲肾上腺素 盐酸盐

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About This Item

经验公式(希尔记法):
C11H17NO3 · HCl
CAS号:
分子量:
247.72
Beilstein:
3917363
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

isoprenaline

製造商/商標名

EDQM

mp

165-175 °C (dec.) (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI 密鑰

IROWCYIEJAOFOW-UHFFFAOYSA-N

基因資訊

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一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

應用

盐酸异丙肾上腺素EP参考标准品的预期用途是欧洲药典规定的实验室测试。

生化/生理作用

β-肾上腺素受体激活剂;增加胞质cAMP。

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能适用相应的销售限制条件。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Peter Kubuš et al.
Circulation. Arrhythmia and electrophysiology, 7(2), 218-223 (2014-02-04)
Data on the results and clinical effect of an invasive risk stratification strategy in asymptomatic young patients with the Wolff-Parkinson-White electrocardiographic pattern are scarce. Eighty-five consecutive patients aged<18 years with a Wolff-Parkinson-White pattern and persistent preexcitation at maximum exercise undergoing
Marianne Tare et al.
Clinical science (London, England : 1979), 127(9), 559-569 (2014-05-13)
Intrauterine inflammation is a major contributor to preterm birth and has adverse effects on preterm neonatal cardiovascular physiology. Cardiomyocyte maturation occurs in late gestation in species such as humans and sheep. We tested the hypothesis that intrauterine inflammation has deleterious
Inbal Rachmin et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5902-5907 (2014-04-09)
ErbB2 interacting protein (Erbin) is a widely expressed protein and participates in inhibition of several intracellular signaling pathways. Its mRNA has been found to be present in relatively high levels in the heart. However, its physiological role in the heart
Chrishan S Samuel et al.
Hypertension (Dallas, Tex. : 1979), 64(2), 315-322 (2014-05-29)
Relaxin is a naturally occurring peptide hormone that mediates systemic hemodynamic and renal adaptive changes during pregnancy and abrogates aberrant scar tissue formation (fibrosis) in diverse pathogeneses. However, its efficacy relative to renin–angiotensin system blockade, the most effective antifibrotic strategy
Christiane Neuber et al.
The Journal of pharmacology and experimental therapeutics, 349(1), 39-46 (2014-01-17)
Stimulation of myocardial β(1)-adrenoceptors (AR) is a major mechanism that increases cardiac function. We investigated the functional consequences of genetic β(1)-AR knockdown in three-dimensional engineered heart tissue (EHT). For β(1)-AR knockdown, short interfering RNA (siRNA) sequences targeting specifically the β(1)-AR

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